Yang D Y, Ren Y J, Fu Y, Xie Y, Nong X, Gu X B, Wang S X, Peng X R, Yang G Y
Department of Parasitology,College of Veterinary Medicine, Sichuan Agricultural University,Ya'an625014,China.
Sichuan Academy of Animal Science,Chengdu,610066,China.
J Helminthol. 2015 Jul;89(4):502-5. doi: 10.1017/S0022149X14000236. Epub 2014 Apr 2.
Cysticercosis is caused by infections with embryonated eggs of the tapeworm Taenia pisiformis. Knowledge of the genetic characteristics of T. pisiformis could be applied to study the epidemiology and transmission of this parasite. In this study, 61 isolates of intraperitoneal cysticerci from eight geographically distinct regions in Sichuan province, China, were subjected to a molecular analysis in order to determine their intra-regional genetic characteristics. Partial sequences of the mitochondrial cytochrome c oxidase subunit I (cox1, 1427 bp) and NADH dehydrogenase 1 (nad1, 738 bp) were concatenated. Five haplotypes were identified, and 89.04% of total genetic variation was found in collections of T. pisiformis isolates from a single region. According to the phylogenetic reconstruction, the T. pisiformis isolates from eight regions did not form geographical clusters. Our study highlights the genetic characteristics of T. pisiformis with the aim of accelerating the genetic research and control of cysticercosis.
囊尾蚴病是由感染豆状带绦虫的含胚卵引起的。了解豆状带绦虫的遗传特征可用于研究这种寄生虫的流行病学和传播。在本研究中，对来自中国四川省八个地理区域的61株腹腔囊尾蚴进行了分子分析，以确定它们在区域内的遗传特征。将线粒体细胞色素c氧化酶亚基I（cox1，1427 bp）和烟酰胺腺嘌呤二核苷酸脱氢酶1（nad1，738 bp）的部分序列拼接在一起。鉴定出五种单倍型，并且在来自单个区域的豆状带绦虫分离株集合中发现了89.04%的总遗传变异。根据系统发育重建，来自八个区域的豆状带绦虫分离株未形成地理聚类。我们的研究突出了豆状带绦虫的遗传特征，旨在加速囊尾蚴病的遗传研究和控制。
