Reinertsen Ingerid, Lindseth Frank, Askeland Christian, Iversen Daniel Høyer, Unsgård Geirmund
SINTEF, Medical Technology, P.B. 4760 Sluppen, 7465, Trondheim, Norway,
Acta Neurochir (Wien). 2014 Jul;156(7):1301-10. doi: 10.1007/s00701-014-2052-6. Epub 2014 Apr 3.
Brain-shift is a major source of error in neuronavigation systems based on pre-operative images. In this paper, we present intra-operative correction of brain-shift using 3D ultrasound.
The method is based on image registration of vessels extracted from pre-operative MRA and intra-operative power Doppler-based ultrasound and is fully integrated in the neuronavigation software.
We have performed correction of brain-shift in the operating room during surgery and provided the surgeon with updated information. Here, we present data from seven clinical cases with qualitative and quantitative error measures.
The registration algorithm is fast enough to provide the surgeon with updated information within minutes and accounts for large portions of the experienced shift. Correction of brain-shift can make pre-operative data like fMRI and DTI reliable for a longer period of time and increase the usefulness of the MR data as a supplement to intra-operative 3D ultrasound in terms of overview and interpretation.
脑移位是基于术前图像的神经导航系统中误差的主要来源。在本文中，我们展示了使用三维超声进行术中脑移位校正。
该方法基于从术前磁共振血管造影（MRA）提取的血管与术中基于功率多普勒的超声的图像配准，并完全集成在神经导航软件中。
我们已在手术室手术期间进行了脑移位校正，并为外科医生提供了更新信息。在此，我们展示了来自七个临床病例的定性和定量误差测量数据。
配准算法速度足够快，能够在数分钟内为外科医生提供更新信息，并能校正大部分已观察到的移位。脑移位校正可使功能磁共振成像（fMRI）和扩散张量成像（DTI）等术前数据在更长时间内保持可靠，并在整体观察和解读方面提高磁共振数据作为术中三维超声补充的有用性。
