Moustou Aikaterini-Evangelia, Kakourou Talia, Masouri Sofia, Alexopoulos Alexis, Sachlas Athanasios, Antoniou Christina
1st Department of Dermatology, University of Athens Medical School, Andreas Sygros Hospital, Athens, Greece.
Int J Dermatol. 2014 Dec;53(12):1447-53. doi: 10.1111/ijd.12225. Epub 2014 Apr 2.
Childhood and adolescent psoriasis is not an uncommon disease, but epidemiological information from a large series of studies is still lacking.
Our purpose was to present the demographics, clinical features, and outcome of psoriasis appearing in Greek patients from infants up to adolescents.
We conducted a retrospective analysis of 842 children and adolescents who diagnosed with psoriasis over a period of twenty years.
The mean age of psoriasis onset was 7.33 years, and the sex distribution was equal between boys and girls. Plaque-type psoriasis was the most frequent type (82.1%), followed by perianal, inverse, and guttate. The limbs and the scalp were the main body areas affected. The affected body surface area (BSA) was more than 10% in only 1.7% of patients, and the overall disease manifestations were considered to be mild. Psoriatic nails were detected in 11.8% of patients, while psoriatic arthritis in only six (0.7%) patients. An additional autoimmune disease was present in 3.8% of patients, and 16.7% had a positive family history for first-degree relatives. The main choice of therapy was topical treatment.
Gender distribution, type of psoriasis, and body area affection is almost the same as in adults. Most of the patients presented with mild disease of little extent, possibly indicating the favorable effect of sun in a Mediterranean country. The most often prescribed treatment for the majority of patients was topical.
儿童和青少年银屑病并非罕见疾病，但仍缺乏大量系列研究的流行病学信息。
我们的目的是呈现希腊从婴儿到青少年患者中银屑病的人口统计学特征、临床特征及转归。
我们对20年间诊断为银屑病的842名儿童和青少年进行了回顾性分析。
银屑病发病的平均年龄为7.33岁，男女性别分布均等。斑块型银屑病是最常见的类型（82.1%），其次是肛周、反向和点滴状。四肢和头皮是主要受累身体部位。仅1.7%的患者受累体表面积（BSA）超过10%，总体疾病表现被认为较轻。11.8%的患者检测到银屑病甲，而仅6例（0.7%）患者有银屑病关节炎。3.8%的患者存在另一种自身免疫性疾病，16.7%的患者一级亲属有阳性家族史。主要治疗选择是局部治疗。
性别分布、银屑病类型和身体部位受累情况与成人几乎相同。大多数患者表现为轻度且范围较小的疾病，这可能表明在地中海国家阳光有有益作用。大多数患者最常开具的治疗是局部治疗。
