Wasiak J, Paul E, Lee S J, Mahar P, Pfitzer B, Spinks A, Cleland H, Gabbe B
Victorian Adult Burns Service and School of Public Health and Preventive Medicine, Monash University, The Alfred Hospital, Commercial Road, Melbourne, Victoria, Australia.
Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, The Alfred Centre, Commercial Road, Melbourne, Australia.
Injury. 2014 Sep;45(9):1459-64. doi: 10.1016/j.injury.2014.02.018. Epub 2014 Feb 20.
To describe patients' generic health status and health-related quality of life (HRQoL) 12-months following admission to a state-wide burns service.
A total of 114 injured adults with >10% total body surface area burned (TBSA) or burns less than 10% TBSA to smaller anatomical areas such as the hands and feet participated in this study. Retrospective assessment of pre-burn injury status and prospective assessment of generic health and HRQoL were followed up at 3, 6 and 12-months after injury using the 36-item Short Form Health Survey (SF-36 v.2) and Burns Specific Health Scale-Brief (BSHS-B). The SF-36 v.2 was administered retrospectively during the initial hospital stay to assess pre-injury HRQoL. Changes in instruments scores were assessed using multilevel mixed effects regression models. Mean scores were compared over time and between severity groups as defined by <10%, 10-30% and >30% TBSA.
For the overall sample, the SF-36 v.2 physical component scale (PCS) score between 3 and 12-months post-burn injury were significantly lower than pre-injury scores (p<0.01), with no significant change over time for the mental component scale (MCS) (p=0.36). Significant %TBSA-burden by time interactions highlighted changes from pre-burn injury in overall PCS (p=0.02), physical functioning (p<0.001) and role-physical (p=0.03), with subscales worse for the TBSA >30% group. With respect to the BSHS-B, significant improvement from 3 to 12-months post-burn injury was seen for the entire sample in simple abilities (p<0.001), hand function (p=0.001), work (p=0.01), and treatment regime (p=0.004) subscales. The TBSA >30% group showed a greater rate of improvement in simple abilities (p=0.01) and hand function (p=0.005) between 3 and 12 months post-burn injury.
Whilst certain HRQoL measures improve over the 12-months, in most cases they do not reach pre-morbid levels. Patients face ongoing challenges regarding their physical and psychosocial recovery 12-months post-burn injury with respect to generic health and burn-specific health. These challenges vary at different time periods over the 12-month post-burn period, and may provide windows of opportunity in which to address ongoing issues.
描述在全州范围烧伤服务机构入院12个月后患者的一般健康状况和健康相关生活质量(HRQoL)。
共有114名成年烧伤患者参与本研究,这些患者的烧伤总面积(TBSA)>10%,或TBSA小于10%但烧伤部位为如手和脚等较小解剖区域。采用36项简短健康调查问卷(SF-36 v.2)和烧伤特异性健康量表简表(BSHS-B),对烧伤前损伤状况进行回顾性评估,并在受伤后3、6和12个月对一般健康状况和HRQoL进行前瞻性评估。在初次住院期间对SF-36 v.2进行回顾性施测,以评估伤前HRQoL。使用多级混合效应回归模型评估量表分数的变化。比较不同时间以及根据TBSA<10%、10 - 30%和>30%定义的严重程度组之间的平均分数。
对于总体样本,烧伤后3至12个月的SF-36 v.2身体成分量表(PCS)分数显著低于伤前分数(p<0.01),而心理成分量表(MCS)分数随时间无显著变化(p = 0.36)。TBSA百分比与时间的显著交互作用突出显示了总体PCS(p = 0.02)、身体功能(p<0.001)和身体角色(p = 0.03)从烧伤前起的变化,TBSA>30%组的各子量表情况更差。关于BSHS-B,整个样本在烧伤后3至12个月期间,在简单能力(p<0.001)、手部功能(p = 0.001)、工作(p = 0.01)和治疗方案(p = 0.004)子量表上有显著改善。TBSA>30%组在烧伤后3至12个月期间,在简单能力(p = 0.01)和手部功能(p = 0.005)方面显示出更大的改善率。
虽然某些HRQoL指标在12个月内有所改善,但在大多数情况下并未达到病前水平。烧伤后12个月,患者在一般健康状况和烧伤特异性健康方面的身体和心理社会恢复仍面临持续挑战。这些挑战在烧伤后12个月的不同时间段有所不同,可能为解决持续存在的问题提供机会窗口。