Levina L D, Ambalov Iu M, Zueva V V, Romanova E B
Lab Delo. 1989(3):55-7.
Haptoglobin (Hp) phenotype distribution has been examined in 193 patients with an acute icteric form of hepatitis B (HBsAg+), in 36 chronic HBsAg carriers, and in 317 normal controls. The incidence rates of three Hp types have been virtually the same in the acute patients and in the controls. In chronic HBsAg carriers the Hp 1-1 type has been detected 3 times more frequently than in acute hepatitis B patients and 4 times more frequently than in normal subjects. The authors suppose that the presence of Hp 1-1 type is one of the genetic factors that determine (in case of a hepatitis B infection) the liability to the development of a chronic subclinical infectious process and not of an acute form of this infection.
已对193例急性黄疸型乙型肝炎患者（HBsAg阳性）、36例慢性HBsAg携带者和317名正常对照者的触珠蛋白（Hp）表型分布进行了检测。三种Hp类型的发生率在急性患者和对照者中几乎相同。在慢性HBsAg携带者中，Hp 1-1型的检出频率比急性乙型肝炎患者高3倍，比正常受试者高4倍。作者推测，Hp 1-1型的存在是决定（在乙型肝炎感染的情况下）发生慢性亚临床感染过程而非这种感染的急性形式的易感性的遗传因素之一。
