Age-related effects of converting enzyme inhibitors: a commentary.

Experience with angiotensin converting enzyme (ACE) inhibitor drugs as with other antihypertensive agents, is limited in the elderly. Nevertheless, they appear effective and well tolerated but without evidence to suggest that they have any special role in the elderly compared to a younger age group. Most are excreted through the kidney and dosage should be reduced to match glomerular function. ACE inhibitors seem likely to be used increasingly in the elderly, especially when more traditional agents are contraindicated because of concomitant disease.