Ball S G
Department of Cardiovascular Studies, University of Leeds, England.
J Cardiovasc Pharmacol. 1988;12 Suppl 8:S105-8.
Experience with angiotensin converting enzyme (ACE) inhibitor drugs as with other antihypertensive agents, is limited in the elderly. Nevertheless, they appear effective and well tolerated but without evidence to suggest that they have any special role in the elderly compared to a younger age group. Most are excreted through the kidney and dosage should be reduced to match glomerular function. ACE inhibitors seem likely to be used increasingly in the elderly, especially when more traditional agents are contraindicated because of concomitant disease.
与其他抗高血压药物一样，老年人使用血管紧张素转换酶（ACE）抑制剂的经验有限。然而，它们似乎有效且耐受性良好，但没有证据表明与年轻人群相比，它们在老年人中有任何特殊作用。大多数通过肾脏排泄，应减少剂量以匹配肾小球功能。ACE抑制剂在老年人中的使用可能会越来越多，尤其是当由于合并症而禁忌使用更传统的药物时。
