Banerjee Joyashree, Roy Anindya, Singhamahapatra Anilbaran, Dey Pranab Kumar, Ghosal Achyut, Das Anubrata
Assistant Professor, Department of Physiology, R.G. Kar Medical College , Kolkata, India .
Professor and Head, Department of Physiology, R.G. Kar Medical College , Kolkata, India .
J Clin Diagn Res. 2014 Feb;8(2):12-4. doi: 10.7860/JCDR/2014/7306.3993. Epub 2014 Feb 3.
Association between obesity and asthma has been reported widely, with disparity between males and females. Epidemiological data which indicate that obesity precedes development of asthma and increases the prevalence and incidence of asthma, raises the possibility of a causal association.
To find out the association, including gender differences, between Body Mass Index (BMI) and lung functions in non-asthmatics identified by spirometric protocols.
A retrospective analysis was conducted of the spirometry results obtained between October 2012 and March 2013 for six months. Participants were referred by a variety of medical specialties to the pulmonary function laboratory in Physiology department, R.G. Kar Medical College, Kolkata, India of the 590 test results recorded in the study database 424 non-asthmatic subjects were reviewed.
Significant differences in the spirometric parameters, measured as a percentage of predicted were evident between male and female. Among obese subjects significant correlation is found between BMI and pulmonary function values, FEV1(r = -0.531, p=0.009); FEF25-75% (r= -0.653, p=0.001); FEV1/FVC (r= - 0.603, p=0.002). Significant association was found between BMI and lung function in obese female but not in obese male.
Association was found between indices of spirometry and BMI in non-asthmatic obese group along with a gender disparity.
肥胖与哮喘之间的关联已被广泛报道，且存在性别差异。流行病学数据表明肥胖先于哮喘发生，并增加哮喘的患病率和发病率，这增加了因果关联的可能性。
通过肺活量测定方案确定非哮喘患者的体重指数（BMI）与肺功能之间的关联，包括性别差异。
对2012年10月至2013年3月六个月间获得的肺活量测定结果进行回顾性分析。参与者由多个医学专科转诊至印度加尔各答R.G. Kar医学院生理系肺功能实验室。在研究数据库记录的590份测试结果中，对424名非哮喘受试者进行了评估。
以预测值百分比衡量的肺活量测定参数在男性和女性之间存在显著差异。在肥胖受试者中，BMI与肺功能值之间存在显著相关性，FEV1（r = -0.531，p = 0.009）；FEF25 - 75%（r = -0.653，p = 0.001）；FEV1/FVC（r = -0.603，p = 0.002）。在肥胖女性中，BMI与肺功能之间存在显著关联，而在肥胖男性中则不存在。
在非哮喘肥胖组中，肺活量测定指标与BMI之间存在关联，且存在性别差异。
