用于再生医学的电纺丝：主要主题综述
Electrospinning for regenerative medicine: a review of the main topics.
作者信息
Braghirolli Daikelly I, Steffens Daniela, Pranke Patricia
机构信息
Hematology and Stem Cell Laboratory, Faculty of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre 90610-000, Brazil; Post Graduate Program in Physiology, Federal University of Rio Grande do Sul, Porto Alegre 90010-170, Brazil.
Hematology and Stem Cell Laboratory, Faculty of Pharmacy, Federal University of Rio Grande do Sul, Porto Alegre 90610-000, Brazil; Post Graduate Program in Physiology, Federal University of Rio Grande do Sul, Porto Alegre 90010-170, Brazil; Stem Cell Research Institute, Porto Alegre 90020-010, Brazil.
出版信息
Drug Discov Today. 2014 Jun;19(6):743-53. doi: 10.1016/j.drudis.2014.03.024. Epub 2014 Apr 2.
Electrospun fibers are promising tissue engineering scaffolds that offer the cells an environment that mimics the native extracellular matrix. Fibers with different characteristics can be produced by the electrospinning technique according to the needs of the tissue to be repaired. In this review, the process of electrospinning was examined, providing a description of the common techniques used for the physicochemical and biological characterization of electrospun fibers. The review also discusses the potential applications of electrospun scaffolds for tissue engineering, based on scientific literature.
静电纺丝纤维是很有前景的组织工程支架，能为细胞提供一个模拟天然细胞外基质的环境。根据待修复组织的需求，可通过静电纺丝技术制备具有不同特性的纤维。在这篇综述中，对静电纺丝过程进行了研究，描述了用于静电纺丝纤维物理化学和生物学表征的常用技术。该综述还基于科学文献讨论了静电纺丝支架在组织工程中的潜在应用。
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