Sastre-Garau X, Bosq J, Carlu C, Flamant F, Caillaud J M
Laboratoire d'Histopathologie, Institut Curie, Paris.
Ann Pathol. 1989;9(2):109-14.
Histopathologic study of 20 cases of synovial sarcoma (S.S.) in children has been conducted to evaluate the usefulness of immunohistochemistry in the diagnostic assessment of this tumor. Two of the 6 antibodies studied have been found to be the most informative: staining for keratin and vimentin proteins has been observed in most cases, outlining the epithelial and sarcomatous components of this tumor. The results are in accordance with those already described for S.S. in adults. The presence of cytokeratins in S.S. is discordant with classical histogenetic conceptions.
对20例儿童滑膜肉瘤(S.S.)进行了组织病理学研究,以评估免疫组织化学在该肿瘤诊断评估中的实用性。在所研究的6种抗体中,有2种被发现最具信息价值:在大多数病例中均观察到角蛋白和波形蛋白的染色,勾勒出该肿瘤的上皮和肉瘤成分。结果与已报道的成人滑膜肉瘤结果一致。滑膜肉瘤中细胞角蛋白的存在与经典的组织发生学概念不一致。