Leader M, Patel J, Collins M, Kristin H
Cancer. 1987 Jun 15;59(12):2096-8. doi: 10.1002/1097-0142(19870615)59:12<2096::aid-cncr2820591222>3.0.co;2-c.
The histogenesis of synovial sarcomas remains controversial. An origin from epithelium, synovium, or synovial-related cells and neural tissue has been advanced. Using a combination of a cytokeratin (epithelial marker) antibody and a vimentin (mesenchymal marker) antibody, this study suggests that a synovial sarcoma might be regarded as a carcinosarcoma. It also highlights the diagnostic utility of those antibodies in the diagnosis of synovial sarcomas.
滑膜肉瘤的组织发生仍存在争议。有观点认为其起源于上皮、滑膜或滑膜相关细胞以及神经组织。本研究通过联合使用细胞角蛋白(上皮标志物)抗体和波形蛋白(间充质标志物)抗体,提示滑膜肉瘤可能被视为癌肉瘤。同时也强调了这些抗体在滑膜肉瘤诊断中的应用价值。