Kulka M, Bełtowski J, Kluciński W, Orłowska M, Kołodziejska J, Kleczkowski M
Pol J Vet Sci. 2014;17(1):143-7. doi: 10.2478/pjvs-2014-0019.
The objective of this study was to investigate paraoxonase-1 (PON-1) activity in different lactation stages. The study was conducted on Holstein--Friesian dairy cows in 2nd and 3rd lactation. A significant decrease in paraoxonase activity was found in the postpartum period and during peak of lactation. Serum triglyceride and cholesterol concentration were also markedly reduced during postpartum period. The concentrations of uric acid in serum was 23% higher during lactation peak in comparison with dry and postpartum period. The results indicate that lower serum paraoxonase activity and higher concentration of uric acid are associated with oxidative character of transition period and lipid functional antioxidative protection during intensive milk production.
本研究的目的是调查不同泌乳阶段的对氧磷酶-1（PON-1）活性。该研究以处于第二和第三泌乳期的荷斯坦-弗里生奶牛为对象。研究发现，产后和泌乳高峰期对氧磷酶活性显著降低。产后血清甘油三酯和胆固醇浓度也明显降低。与干奶期和产后相比，泌乳高峰期血清尿酸浓度高23%。结果表明，较低的血清对氧磷酶活性和较高的尿酸浓度与围产期的氧化特性以及高强度产奶期间的脂质功能性抗氧化保护有关。
