从瑞士人类分离出的肠炎沙门氏菌哈达尔、肯塔基、维尔乔、施瓦岑格伦德和4,5,12:i:-血清型中的喹诺酮耐药机制，以及哈达尔血清型中新型qnrD变体qnrD2的鉴定
Quinolone resistance mechanisms in Salmonella enterica serovars Hadar, Kentucky, Virchow, Schwarzengrund, and 4,5,12:i:-, isolated from humans in Switzerland, and identification of a novel qnrD variant, qnrD2, in S. Hadar.
作者信息
Abgottspon Helga, Zurfluh Katrin, Nüesch-Inderbinen Magdalena, Hächler Herbert, Stephan Roger
机构信息
Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
Institute for Food Safety and Hygiene, Vetsuisse Faculty, University of Zurich, Zurich, Switzerland
出版信息
Antimicrob Agents Chemother. 2014 Jun;58(6):3560-3. doi: 10.1128/AAC.02404-14. Epub 2014 Apr 14.
Abstract
Human isolates of Salmonella enterica serovars Hadar, Kentucky, Virchow, Schwarzengrund, and the monophasic variant of S. Typhimurium, Salmonella enterica subsp. enterica serovar 4,5,12:i:- were examined for mutations within the quinolone resistance target genes gyrA, gyrB, parC, and parE and for plasmid-mediated resistance genes. Differences were observed among the serovars. A novel variant of qnrD, qnrD2, was detected in an S. Hadar isolate.
摘要
对肠炎沙门氏菌血清型哈达尔、肯塔基、维尔乔、施瓦岑格鲁德的人类分离株以及鼠伤寒沙门氏菌单相变体肠炎沙门氏菌亚种肠炎血清型4,5,12:i:-进行了喹诺酮抗性靶基因gyrA、gyrB、parC和parE内的突变以及质粒介导抗性基因的检测。各血清型之间存在差异。在一株哈达尔沙门氏菌分离株中检测到一种新型的qnrD变体qnrD2。
相似文献
1
Quinolone resistance mechanisms in Salmonella enterica serovars Hadar, Kentucky, Virchow, Schwarzengrund, and 4,5,12:i:-, isolated from humans in Switzerland, and identification of a novel qnrD variant, qnrD2, in S. Hadar.从瑞士人类分离出的肠炎沙门氏菌哈达尔、肯塔基、维尔乔、施瓦岑格伦德和4,5,12:i:-血清型中的喹诺酮耐药机制，以及哈达尔血清型中新型qnrD变体qnrD2的鉴定
Antimicrob Agents Chemother. 2014 Jun;58(6):3560-3. doi: 10.1128/AAC.02404-14. Epub 2014 Apr 14.
2
Hotspots sequences of gyrA, gyrB, parC, and parE genes encoded for fluoroquinolones resistance from local Salmonella Typhi strains in Jakarta.来自雅加达本地伤寒沙门氏菌的氟喹诺酮类药物耐药基因 gyrA、gyrB、parC 和 parE 的热点序列。
BMC Microbiol. 2022 Oct 18;22(1):250. doi: 10.1186/s12866-022-02666-z.
3
Prevalence of mutations within the quinolone resistance-determining region of gyrA, gyrB, parC, and parE and association with antibiotic resistance in quinolone-resistant Salmonella enterica.喹诺酮耐药决定区gyrA、gyrB、parC和parE内突变的发生率以及与耐喹诺酮肠炎沙门氏菌抗生素耐药性的关联
Antimicrob Agents Chemother. 2004 Oct;48(10):4012-5. doi: 10.1128/AAC.48.10.4012-4015.2004.
4
Quinolone Resistance Mechanisms Among Salmonella enterica in Malaysia.马来西亚肠炎沙门氏菌中的喹诺酮耐药机制
Microb Drug Resist. 2016 Jun;22(4):259-72. doi: 10.1089/mdr.2015.0158. Epub 2015 Dec 18.
5
Isolation and characterization of small qnrS1-carrying plasmids from imported seafood isolates of Salmonella enterica that are highly similar to plasmids of clinical isolates.从进口海产品肠炎沙门氏菌分离株中分离并鉴定携带小qnrS1的质粒，这些质粒与临床分离株的质粒高度相似。
FEMS Immunol Med Microbiol. 2012 Apr;64(3):429-32. doi: 10.1111/j.1574-695X.2011.00921.x. Epub 2012 Jan 11.
6
Detection of a Novel qnrB19-Carrying Plasmid Variant Mediating Decreased Fluoroquinolone Susceptibility in Salmonella enterica Serovar Hadar.在肠炎沙门氏菌哈达尔血清型中检测到一种携带新型qnrB19的质粒变体，该变体介导氟喹诺酮敏感性降低
Microb Drug Resist. 2017 Apr;23(3):280-284. doi: 10.1089/mdr.2016.0067. Epub 2016 Jul 12.
7
Mechanisms of resistance in nontyphoidal Salmonella enterica strains exhibiting a nonclassical quinolone resistance phenotype.表现出非经典喹诺酮耐药表型的非伤寒肠炎沙门氏菌菌株的耐药机制。
Antimicrob Agents Chemother. 2009 Sep;53(9):3832-6. doi: 10.1128/AAC.00121-09. Epub 2009 Jul 13.
8
Presence of plasmid-mediated quinolone resistance determinants and mutations in gyrase and topoisomerase in Salmonella enterica isolates with resistance and reduced susceptibility to ciprofloxacin.对环丙沙星耐药和敏感性降低的肠炎沙门氏菌分离株中质粒介导的喹诺酮耐药决定子以及gyrase和拓扑异构酶中的突变情况。
Diagn Microbiol Infect Dis. 2016 May;85(1):85-9. doi: 10.1016/j.diagmicrobio.2016.01.016. Epub 2016 Jan 26.
9
Plasmid-mediated quinolone resistance determinant qnrS1 found in Salmonella enterica strains isolated in the UK.在英国分离出的肠炎沙门氏菌菌株中发现的质粒介导喹诺酮抗性决定子qnrS1。
J Antimicrob Chemother. 2007 Jun;59(6):1071-5. doi: 10.1093/jac/dkm081. Epub 2007 Apr 12.
10
High-level resistance to fluoroquinolones linked to mutations in gyrA, parC, and parE in Salmonella enterica serovar Schwarzengrund isolates from humans in Taiwan.台湾地区人类分离的肠炎沙门氏菌施瓦岑贝格血清型菌株中，与gyrA、parC和parE基因突变相关的氟喹诺酮类高水平耐药性。
Antimicrob Agents Chemother. 2005 Feb;49(2):862-3. doi: 10.1128/AAC.49.2.862-863.2005.
引用本文的文献
1
Emerging Resistance and Virulence Patterns in : Insights into Silver Nanoparticles as an Antimicrobial Strategy.新兴的耐药性和毒力模式：对银纳米颗粒作为抗菌策略的见解
Antibiotics (Basel). 2025 Jan 7;14(1):46. doi: 10.3390/antibiotics14010046.
2
Mutational Diversity in the Quinolone Resistance-Determining Regions of Type-II Topoisomerases of Serovars.血清型II型拓扑异构酶喹诺酮耐药决定区的突变多样性
Antibiotics (Basel). 2021 Nov 26;10(12):1455. doi: 10.3390/antibiotics10121455.
3
Genotypic Diversity of Ciprofloxacin Nonsusceptibility and Its Relationship with Minimum Inhibitory Concentrations in Nontyphoidal Clinical Isolates in Taiwan.台湾非伤寒临床分离株中对环丙沙星不敏感的基因型多样性及其与最低抑菌浓度的关系
Antibiotics (Basel). 2021 Nov 11;10(11):1383. doi: 10.3390/antibiotics10111383.
4
Chromosomal and plasmid-mediated fluoroquinolone resistance in human Salmonella enterica infection in Ghana.加纳人感染沙门氏菌中染色体和质粒介导的氟喹诺酮耐药性。
BMC Infect Dis. 2019 Oct 28;19(1):898. doi: 10.1186/s12879-019-4522-1.
5
Transmission of ciprofloxacin resistance in mediated by a novel type of conjugative helper plasmids.介导的环丙沙星耐药性的传播是由一种新型的可移动辅助质粒介导的。
Emerg Microbes Infect. 2019;8(1):857-865. doi: 10.1080/22221751.2019.1626197.
6
Evolution and transmission of a conjugative plasmid encoding both ciprofloxacin and ceftriaxone resistance in Salmonella.沙门氏菌中同时编码对环丙沙星和头孢曲松耐药性的可接合质粒的进化和传播。
Emerg Microbes Infect. 2019;8(1):396-403. doi: 10.1080/22221751.2019.1585965.
7
Phenotypic and genotypic characteristics of with non-susceptibility to quinolones isolated from environmental samples on pig farms.从猪场环境样本中分离出的对喹诺酮类药物不敏感的[具体对象]的表型和基因型特征。 （注：原文中“with non-susceptibility to quinolones isolated from environmental samples on pig farms”前缺少具体所指对象，翻译时根据语境补充了[具体对象]，以使译文完整通顺）
Porcine Health Manag. 2019 Feb 28;5:9. doi: 10.1186/s40813-019-0116-y. eCollection 2019.
8
Identification and Characterization of Conjugative Plasmids That Encode Ciprofloxacin Resistance in Salmonella.鉴定和表征编码沙门氏菌中环丙沙星耐药性的可接合质粒。
Antimicrob Agents Chemother. 2018 Jul 27;62(8). doi: 10.1128/AAC.00575-18. Print 2018 Aug.
9
Draft Genomic Analysis of an Avian Multidrug Resistant Isolate Carrying .携带……的禽类多重耐药分离株的基因组分析草案
Front Microbiol. 2016 Oct 25;7:1660. doi: 10.3389/fmicb.2016.01660. eCollection 2016.
10
Increasing prevalence of ciprofloxacin-resistant food-borne Salmonella strains harboring multiple PMQR elements but not target gene mutations.携带多种质粒介导喹诺酮耐药（PMQR）元件但无靶基因突变的耐环丙沙星食源沙门氏菌菌株的流行率不断上升。
Sci Rep. 2015 Oct 5;5:14754. doi: 10.1038/srep14754.
本文引用的文献
1
The European Union Summary Report on Antimicrobial Resistance in zoonotic and indicator bacteria from humans, animals and food in 2017/2018.《2017/2018年欧盟关于人畜共患病菌及人类、动物和食物中指示菌的抗菌药物耐药性总结报告》
EFSA J. 2020 Mar 3;18(3):e06007. doi: 10.2903/j.efsa.2020.6007. eCollection 2020 Mar.
2
The European Union summary report on antimicrobial resistance in zoonotic and indicator bacteria from humans, animals and food in 2017.2017年欧盟关于人、动物和食物中动物源及指示性细菌抗菌药物耐药性的总结报告。
EFSA J. 2019 Feb 27;17(2):e05598. doi: 10.2903/j.efsa.2019.5598. eCollection 2019 Feb.
3
The global establishment of a highly-fluoroquinolone resistant Salmonella enterica serotype Kentucky ST198 strain.全球范围内出现高氟喹诺酮耐药的肠炎沙门氏菌肯塔基血清型 198 株。
Front Microbiol. 2013 Dec 18;4:395. doi: 10.3389/fmicb.2013.00395. eCollection 2013.
4
Epidemiology of qnrVC alleles and emergence out of the Vibrionaceae family.qnrVC 等位基因的流行病学及在弧菌科中的出现情况。
J Med Microbiol. 2013 Oct;62(Pt 10):1628-1630. doi: 10.1099/jmm.0.062661-0. Epub 2013 Jun 25.
5
Characterization of Salmonella enterica subsp. enterica serovar 4,[5],12:i:- clones isolated from human and other sources in Switzerland between 2007 and 2011.2007 年至 2011 年间瑞士从人和其他来源分离的沙门氏菌肠炎亚种 4,[5],12:i:- 克隆的特征。
Foodborne Pathog Dis. 2013 Jun;10(6):549-54. doi: 10.1089/fpd.2012.1407. Epub 2013 Apr 24.
6
Antimicrobial resistance patterns and genotypes of Salmonella enterica serovar Hadar strains associated with human infections in Switzerland, 2005-2010.2005-2010 年瑞士人类感染哈达尔血清型肠炎沙门氏菌的耐药模式和基因型分析。
Epidemiol Infect. 2014 Jan;142(1):84-9. doi: 10.1017/S095026881300054X. Epub 2013 Apr 16.
7
Complete nucleotide sequence of pVQS1 containing a quinolone resistance determinant from Salmonella enterica serovar Virchow associated with foreign travel.含有与外国旅行相关的肠炎沙门氏菌血清型 Virchow 喹诺酮类耐药决定因子的 pVQS1 的完整核苷酸序列。
J Antimicrob Chemother. 2012 Aug;67(8):1861-4. doi: 10.1093/jac/dks158. Epub 2012 May 2.
8
International collaborative study on the occurrence of plasmid-mediated quinolone resistance in Salmonella enterica and Escherichia coli isolated from animals, humans, food and the environment in 13 European countries.13 个欧洲国家的动物、人类、食物和环境中分离的食源性沙门氏菌和大肠杆菌中质粒介导的喹诺酮耐药性的国际协同研究。
J Antimicrob Chemother. 2011 Jun;66(6):1278-86. doi: 10.1093/jac/dkr084. Epub 2011 Mar 9.
9
Salmonella enterica serotype Virchow associated with human infections in Switzerland: 2004-2009.瑞士与人类感染相关的肠炎沙门氏菌血清型 Virchow：2004-2009 年。
BMC Infect Dis. 2011 Feb 23;11:49. doi: 10.1186/1471-2334-11-49.
10
Characterization of antimicrobial resistance in Salmonella enterica food and animal isolates from Colombia: identification of a qnrB19-mediated quinolone resistance marker in two novel serovars.哥伦比亚食品和动物源沙门氏菌分离株的抗菌药物耐药性特征：两种新型血清型中存在由 qnrB19 介导的喹诺酮类药物耐药标记物。
FEMS Microbiol Lett. 2010 Dec;313(1):10-9. doi: 10.1111/j.1574-6968.2010.02119.x. Epub 2010 Sep 30.
Zotero 插件