Ahmadimanesh M, Shadnia S, Ghazi-Khansari M
Pharmacology Department, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Int J Occup Environ Med. 2014 Apr;5(2):106-8.
Occupational inhalation exposure to noxious agents is not uncommon. Herein, we present a 26-year-old male student who had accidental acute inhalation exposure to a large quantity of titanium ethanolate and hydrogen chloride in chemistry lab. He was referred to the emergency department of our hospital with low-grade fever, dyspnea, headache, fatigue and myalgia. After 24 hrs of symptomatic treatment (oxygen therapy and acetaminophen), the fever was subsided and the patient discharged home in a good clinical condition. The presented symptoms could be interpreted as a form of metal fume fever. It can therefore be concluded that organo-metallic compound of titanium metal may have the potential to produce metal fume fever in human.
职业性吸入接触有害剂并不罕见。在此,我们报告一名26岁的男学生,他在化学实验室意外急性吸入大量乙醇钛和氯化氢。他因低热、呼吸困难、头痛、乏力和肌痛被转诊至我院急诊科。经过24小时的对症治疗(吸氧和对乙酰氨基酚),体温下降,患者临床状况良好出院。所呈现的症状可被解释为金属烟雾热的一种形式。因此可以得出结论,钛金属的有机金属化合物可能有在人体产生金属烟雾热的潜力。