Viatkin A A, Petrosian L G, Mizikov V M, Vasil'ev S A
Anesteziol Reanimatol. 2013 Nov-Dec(6):17-21.
Neuroprotection could be the aim to use Xenon for general anesthesia. However the experience of Xenon anesthesia in neurosurgery is quite limited. The appraisal of Xenon based anesthesia was accomplished in 12 patients during various brain surgery. Xe in concentration 65% was used to maintenance of anesthesia, other medication was avoided. As a resuIt there were 8 cases of arterial hypertension and 2 cases of superficial hypnotic state. Excitation (n = 3), hyperdynamic reaction (n = 8), PONV (n = 8) were detected in early postoperative period. An analysis of this study suggests a conclusion that studied method of Xenon-based anesthesia is inexpedient for neurosurgery.
神经保护可能是将氙气用于全身麻醉的目的。然而，氙气麻醉在神经外科手术中的经验相当有限。在12例接受各种脑部手术的患者中对基于氙气的麻醉进行了评估。使用浓度为65%的氙气维持麻醉，避免使用其他药物。结果出现了8例动脉高血压和2例浅催眠状态。术后早期检测到兴奋（n = 3）、高动力反应（n = 8）、术后恶心呕吐（n = 8）。该研究的分析表明，基于氙气的麻醉研究方法不适合用于神经外科手术。
