Rylova A V, Gavrilov A G, Lubnin A Iu, Potapov A A
Anesteziol Reanimatol. 2014 Jul-Aug;59(4):19-25.
Despite difficulties in providing xenon anaesthesia, xenon still seems to be attractive for neurosurgical procedures. But data upon its effect on intracranial (ICP) and cerebral perfusion pressure (CPP) remains controversial. We monitored ICP and CPP in patients with or without intracranial hypertension during xenon inhalation in different concentrations. Our results suggest that caution should be used while inhaling xenon in high anaesthetic concentration in patients wiith known intracranial hypertension. We also address new possibilities of xenon use, e.g., for sedation in neurosurgery. The study was supported by Russian Fund for Fundamental Research, grant number 13-04-01640.
尽管提供氙气麻醉存在困难，但氙气对于神经外科手术而言似乎仍具有吸引力。但其对颅内压（ICP）和脑灌注压（CPP）的影响数据仍存在争议。我们在不同浓度氙气吸入期间监测了有或无颅内高压患者的ICP和CPP。我们的结果表明，对于已知患有颅内高压的患者，在高麻醉浓度下吸入氙气时应谨慎。我们还探讨了氙气使用的新可能性，例如在神经外科手术中用于镇静。本研究得到了俄罗斯基础研究基金的支持，资助编号为13 - 04 - 01640。
