Pocock J M, Khun P A, Moore C E, Vuthy S, Stoesser N, Parry C M
Paediatr Int Child Health. 2014 Aug;34(3):227-9. doi: 10.1179/2046905514Y.0000000123. Epub 2014 Apr 21.
Septic arthritis is a rare complication of typhoid fever. A 12-year-old boy without pre-existing disease attended a paediatric hospital in Cambodia with fever and left hip pain. A hip synovial fluid aspirate grew multidrug-resistant Salmonella enterica ser. Typhi with intermediate susceptibility to ciprofloxacin. Arthrotomy, 2 weeks of intravenous ceftriaxone and 4 weeks of oral azithromycin led to resolution of symptoms. The optimum management of septic arthritis in drug-resistant typhoid is undefined.
化脓性关节炎是伤寒热的一种罕见并发症。一名无基础疾病的12岁男孩因发热和左髋疼痛前往柬埔寨一家儿科医院就诊。髋关节滑液抽吸物培养出对多种药物耐药的肠炎沙门氏菌血清型伤寒杆菌,对环丙沙星中度敏感。关节切开术、静脉注射头孢曲松2周和口服阿奇霉素4周后症状得以缓解。耐药伤寒中化脓性关节炎的最佳治疗方法尚不明确。