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一名柬埔寨儿童的髋部感染性关节炎,由对环丙沙星中度敏感的多重耐药性伤寒沙门氏菌引起,采用头孢曲松和阿奇霉素治疗。

Septic arthritis of the hip in a Cambodian child caused by multidrug-resistant Salmonella enterica serovar Typhi with intermediate susceptibility to ciprofloxacin treated with ceftriaxone and azithromycin.

作者信息

Pocock J M, Khun P A, Moore C E, Vuthy S, Stoesser N, Parry C M

出版信息

Paediatr Int Child Health. 2014 Aug;34(3):227-9. doi: 10.1179/2046905514Y.0000000123. Epub 2014 Apr 21.

DOI:10.1179/2046905514Y.0000000123
PMID:24749773
Abstract

Septic arthritis is a rare complication of typhoid fever. A 12-year-old boy without pre-existing disease attended a paediatric hospital in Cambodia with fever and left hip pain. A hip synovial fluid aspirate grew multidrug-resistant Salmonella enterica ser. Typhi with intermediate susceptibility to ciprofloxacin. Arthrotomy, 2 weeks of intravenous ceftriaxone and 4 weeks of oral azithromycin led to resolution of symptoms. The optimum management of septic arthritis in drug-resistant typhoid is undefined.

摘要

化脓性关节炎是伤寒热的一种罕见并发症。一名无基础疾病的12岁男孩因发热和左髋疼痛前往柬埔寨一家儿科医院就诊。髋关节滑液抽吸物培养出对多种药物耐药的肠炎沙门氏菌血清型伤寒杆菌,对环丙沙星中度敏感。关节切开术、静脉注射头孢曲松2周和口服阿奇霉素4周后症状得以缓解。耐药伤寒中化脓性关节炎的最佳治疗方法尚不明确。

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