Gamboa P M, de la Cuesta C G, García B E, Castillo J G, Oehling A
Departamento de Alergologia, Facultad de Medicina, Universidad de Navarra, Pamplona, Spain.
Allergol Immunopathol (Madr). 1989 Mar-Apr;17(2):109-11.
Persulphate salts are among the various chemical substances that can cause occupational diseases in hairdressers. We present the case of a 21 year-old female who worked in a hairdressing salon for five and a half years. Five years prior to consultation, she presented with rhinitic symptoms and wheezing dyspnea which were related with her working environment. The routine laboratory examinations carried out on the patient were found to be normal. Among the various allergic exams performed there was an elevated total IgE. The provocation test with histamine was positive at the concentration of 10 mg/ml, demonstrating mild bronchial hyperreactivity. The test of bronchial exposure to ammonium persulphate was positive with bronchospasm 3-4 hours after this test. With a prior inhalation of betamethasone we were able to block this reaction, but with disodium cromoglycate we were able to block it only partially. We conclude that the patient presented with late onset bronchial asthma due to sensitivity to ammonium persulphate. It has to be pointed out that this patient was a rare case as generally persulphate salts choose to invade and affect the skin. The rarity of this pathology is reflected by the scarce bibliography on this subject.
过硫酸盐是可导致美发师职业病的多种化学物质之一。我们报告一例21岁女性病例，她在一家美发沙龙工作了五年半。在就诊前五年，她出现了鼻炎症状和喘息性呼吸困难，这与她的工作环境有关。对该患者进行的常规实验室检查结果正常。在进行的各种过敏检查中，总IgE升高。组胺激发试验在浓度为10 mg/ml时呈阳性，表明有轻度支气管高反应性。支气管暴露于过硫酸铵的试验呈阳性，试验后3 - 4小时出现支气管痉挛。预先吸入倍他米松能够阻止这种反应，但色甘酸钠只能部分阻止。我们得出结论，该患者因对过硫酸铵敏感而出现迟发性支气管哮喘。必须指出的是，该患者是罕见病例，因为一般来说过硫酸盐会侵袭并影响皮肤。这种病理情况的罕见性体现在关于该主题的文献稀少。
