Liu Yu-Jie, Zhong Rui-Xue, Yang Tian-Jun, Wang Ru-Ru, Wu Chun-Jie
Zhongguo Zhong Yao Za Zhi. 2014 Jan;39(2):338-42.
Though parched Chinese herbal medicines contain less effective or index components, their pharmacological actions do not reduce or even become improved to some extent. However, the current studies related to material basis could not explain the changes in property, flavour and efficacy of parched Chinese herbal medicines. Meanwhile, due to the lack of objective and specific evaluation indexes, the quality evaluation could not reflect features of parched Chinese herbal pieces. Therefore, how to break the bottleneck for the studies on parched Chinese herbal pieces, make further innovation and conduct in-depth studies on the material basis of parched Chinese herbal medicines are common problems that medical scholars are facing. According to the findings in the previous studies, the author proposed to explain the material basis of parched Chinese herbal medicines by studying Maillard reaction and establish specific quality evaluation indexes according to the features of parched Chinese herbal pieces, and conducted relevant studies.
虽然干燥的中药材有效成分或指标性成分含量较低，但其药理作用并未降低，甚至在一定程度上有所增强。然而，目前关于物质基础的研究无法解释干燥中药材的性味和功效变化。同时，由于缺乏客观、具体的评价指标，质量评价无法体现干燥中药饮片的特点。因此，如何突破干燥中药饮片研究的瓶颈，进一步创新并深入研究干燥中药材的物质基础，是医学学者面临的共同问题。根据前期研究结果，作者提出通过研究美拉德反应来解释干燥中药材的物质基础，并根据干燥中药饮片的特点建立具体的质量评价指标，进而开展了相关研究。
