Zaichick Vladimir
Department of Radionuclide Diagnostics, Medical Radiological Research Centre, Koroleva Street 4, Obninsk 249036, Kaluga Region, Russia.
Med Hypotheses. 2014 Jul;83(1):65-8. doi: 10.1016/j.mehy.2014.04.006. Epub 2014 Apr 12.
Several experiments show that prostatic fluid is continuously produced and it is drained from the prostate during urination and ejaculation. The mechanism which causes prostatic fluid to drain from the prostatic acini during urination is currently unclear. Also in current opinion such structures of the prostatic urethra as the urethral crest and the colliculus seminalis have no apparent functional significance. This article describes a mechanism for the draining of the prostatic acini that involves these prostatic urethral structures. It is hypothesized that the prostatic urethra works as a pump using the Venturi effect, in which urine is the carrying or motive liquid during voiding, in order to drain prostatic fluid (the carried liquid) from the acini. The urethral crest and the colliculus seminalis take part in controlling flow rates and liquid pressures for this pump to be effective. The calculated estimation of a pressure drop in the region of the colliculus seminalis during micturition was obtained using morphometric and uroflowmetric data and was used to confirm this hypothesis of prostatic acini drainage. As a consequence of this, a previously unknown function for these intra-prostatic urethral structures is described.
多项实验表明，前列腺液持续产生，并在排尿和射精时从前列腺排出。目前尚不清楚排尿时前列腺液从前列腺腺泡排出的机制。目前的观点还认为，前列腺尿道的诸如尿道嵴和精阜等结构没有明显的功能意义。本文描述了一种涉及这些前列腺尿道结构的前列腺腺泡引流机制。据推测，前列腺尿道利用文丘里效应起到泵的作用，排尿时尿液作为运载或驱动液体，以便从腺泡中排出前列腺液（被运载液体）。尿道嵴和精阜参与控制该泵的流速和液体压力，以使该泵有效工作。利用形态测量学和尿流率测定数据获得了排尿时精阜区域压力降的计算估计值，并用于证实这种前列腺腺泡引流假说。由此，描述了这些前列腺内尿道结构以前未知的功能。
