《巴基斯坦卡拉奇地区小学生骨龄评估中 Greulich & Pyle 图谱的适用性》。
The applicability of the Greulich & Pyle Atlas for bone age assessment in primary school-going children of Karachi, Pakistan.
机构信息
Dr. Arsalan Manzoor Mughal, MBBS, M. Phil Candidate, Senior Lecturer, Department of Anatomy, Dr. Ziauddin Hospital, Ziauddin University, North Nazimabad, Karachi.
Dr. Nuzhat Hassan, MBBS, M.Phil (Anatomy), Professor& Head of Anatomy Department, Dr. Ziauddin Hospital, Ziauddin University, North Nazimabad, Karachi.
出版信息
Pak J Med Sci. 2014 Mar;30(2):409-11.
OBJECTIVE
To assess the degree of applicability of bone age calculated by Greulich & Pyle Atlas in estimation of chronological age for therapeutic and medico legal purposes.
METHODS
Two Hundred and Twenty children (139 males, 81 females) between ages of 56 and 113 months (4.5 to 9.5 years) were randomly selected from 4 primary schools of Shireen Jinnah & Clifton, Karachi. Digital images of hand and wrist radiographs were obtained by a computed radiography at Ziauddin Hospital Clifton. Bone ages were computed using Greulich & Pyle Atlas by radiologists at Ziauddin Hospital, North Nazimabad, Karachi.
RESULTS
On average, the Greulich & Pyle Atlas underestimates chronological age by 6.65 ± 13.47 months in females and 15.78 ± 12.83 months in males (p-values < 0.001). High correlation was found between chronological age and bone age in both genders (Females r=0.778; p-value< 0.001, Males r=0.816; p-value < 0.001).
CONCLUSION
Bone age calculated by Greulich & Pyle Atlas should not be used for estimating chronological age in children of ages 56-113 months in situations where high accuracy is required (e.g. medicolegal cases). However, serial measurements of bone age by this atlas can be used in management of growth related endocrine disorders in these children.
目的
评估 Greulich & Pyle 图谱计算的骨龄在治疗和法医学目的估计实际年龄方面的适用性程度。
方法
从卡拉奇 Shireen Jinnah 和 Clifton 的 4 所小学中随机选择了 220 名年龄在 56 至 113 个月（4.5 至 9.5 岁）的儿童（139 名男性，81 名女性）。在 Ziauddin 医院 Clifton 使用计算机射线照相术获得手部和腕部射线照片的数字图像。由卡拉奇 North Nazimabad 的 Ziauddin 医院的放射科医生使用 Greulich & Pyle 图谱计算骨龄。
结果
平均而言，Greulich & Pyle 图谱在女性中低估实际年龄 6.65 ± 13.47 个月，在男性中低估 15.78 ± 12.83 个月（p 值均 < 0.001）。在两种性别中，实际年龄与骨龄之间均存在高度相关性（女性 r=0.778；p 值 < 0.001，男性 r=0.816；p 值 < 0.001）。
结论
在需要高精度的情况下（例如法医学案例），Greulich & Pyle 图谱计算的骨龄不应用于估计 56-113 个月大的儿童的实际年龄。然而，该图谱的骨龄系列测量可用于这些儿童生长相关内分泌疾病的管理。
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