Prozorova Galina F, Pozdnyakov Alexsandr S, Kuznetsova Nadezhda P, Korzhova Svetlana A, Emel'yanov Artem I, Ermakova Tamara G, Fadeeva Tat'yana V, Sosedova Larisa M
AE Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Sciences, Irkutsk, Russia.
Scientific Center of Reconstructive and Restorative Surgery Siberian Branch of Russian Academy of Medicinal Sciences, Irkutsk, Russia.
Int J Nanomedicine. 2014 Apr 16;9:1883-9. doi: 10.2147/IJN.S57865. eCollection 2014.
New water-soluble nontoxic nanocomposites of nanosized silver particles in a polymer matrix were synthesized by a green chemistry method. Nontoxic poly(1-vinyl-1,2,4-triazole) was used as a stabilizing precursor agent in aqueous medium. Glucose and dimethyl sulfoxide were used as the silver ion-reducing agents to yield silver nanoparticles 2-26 nm and 2-8 nm in size, respectively. The nanocomposites were characterized by transmission electron microscopy, ultraviolet-visible and Fourier transform infrared spectroscopy, X-ray diffraction, atomic absorption, and thermogravimetric data analysis. The nanocomposites showed strong antimicrobial activity against Gram-negative and Gram-positive bacteria.
通过绿色化学方法合成了聚合物基质中纳米银颗粒的新型水溶性无毒纳米复合材料。无毒的聚（1-乙烯基-1,2,4-三唑）在水介质中用作稳定前驱剂。葡萄糖和二甲基亚砜用作银离子还原剂，分别生成尺寸为2-26纳米和2-8纳米的银纳米颗粒。通过透射电子显微镜、紫外可见光谱和傅里叶变换红外光谱、X射线衍射、原子吸收和热重数据分析对纳米复合材料进行了表征。该纳米复合材料对革兰氏阴性菌和革兰氏阳性菌表现出很强的抗菌活性。
