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利用地衣 Parmotrema praesorediosum 合成具有抗菌活性的银纳米粒子。

Synthesis of silver nanoparticles with antibacterial activity using the lichen Parmotrema praesorediosum.

机构信息

School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Selangor, Malaysia ; Faculty of Applied Sciences, Universiti Teknologi MARA Negeri Sembilan, Negeri Sembilan, Malaysia.

School of Chemical Sciences and Food Technology, Faculty of Science and Technology, Universiti Kebangsaan Malaysia, Selangor, Malaysia.

出版信息

Int J Nanomedicine. 2014;9:121-7. doi: 10.2147/IJN.S52306. Epub 2013 Dec 19.

Abstract

Development of a green chemistry process for the synthesis of silver nanoparticles has become a focus of interest. This would offer numerous benefits, including ecofriendliness and compatibility for biomedical applications. Here we report the synthesis of silver nanoparticles from the reduction of silver nitrate and an aqueous extract of the lichen Parmotrema praesorediosum as a reductant as well as a stabilizer. The physical appearance of these silver nanoparticles was characterized using ultraviolet-visible spectroscopy, electron microscopy, energy-dispersive spectroscopy, and X-ray diffraction techniques. The results show that silver nanoparticles synthesized using P. praesorediosum have an average particle size of 19 nm with a cubic structure. The antibacterial activity of the synthesized silver nanoparticles was tested against eight micro-organisms using the disk diffusion method. The results reveal that silver nanoparticles synthesized using P. praesorediosum have potential antibacterial activity against Gram-negative bacteria.

摘要

银纳米粒子的绿色化学合成工艺的发展已成为研究热点。这将带来许多益处,包括生态友好性和生物医学应用的兼容性。在这里,我们报告了从硝酸银和地衣 Parmotrema praesorediosum 的水提物作为还原剂和稳定剂还原合成银纳米粒子。使用紫外-可见光谱、电子显微镜、能谱和 X 射线衍射技术对这些银纳米粒子的物理外观进行了表征。结果表明,使用 P. praesorediosum 合成的银纳米粒子具有平均粒径为 19nm 的立方结构。采用圆盘扩散法测定了所合成的银纳米粒子对 8 种微生物的抗菌活性。结果表明,使用 P. praesorediosum 合成的银纳米粒子对革兰氏阴性菌具有潜在的抗菌活性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/840d/3872223/ad1965132c9c/ijn-9-121Fig1.jpg

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