Yaxley Julian, Chakravarty Bhaskar
is a medical student, Griffith University, Gold Coast, Queensland.
Aust Fam Physician. 2014 May;43(5):301-5.
The eradication of Helicobacter pylori (H. pylori) can be challenging in certain circumstances. There is no current first-line therapy that is curative in all patients.
OBJECTIVE: This article summaries the role of emerging novel therapies in the treatment of H. pylori. Known as sequential therapy and salvage therapy, these new therapeutic strategies are thought to produce eradication rates superior to currently recommended first-line therapies. This article outlines the growing body of evidence supporting their efficacy.
Sequential therapy and salvage therapy have emerged recently as alternative regimens for the eradication of H. pylori. Although current guidelines continue to recommend established therapies for first-line management of H. pylori, general practitioners should be aware of these new strategies such that these options could be applied when traditional therapy fails.
在某些情况下，根除幽门螺杆菌（H. pylori）可能具有挑战性。目前尚无对所有患者都有效的一线治疗方法。
本文总结了新兴的新型疗法在幽门螺杆菌治疗中的作用。这些新的治疗策略被称为序贯疗法和挽救疗法，被认为能产生高于目前推荐的一线疗法的根除率。本文概述了支持其疗效的越来越多的证据。
序贯疗法和挽救疗法最近已成为根除幽门螺杆菌的替代方案。尽管目前的指南继续推荐既定疗法用于幽门螺杆菌的一线管理，但全科医生应了解这些新策略，以便在传统疗法失败时可以应用这些选择。
