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腰椎穿刺初压并非儿童颅内压的可靠测量指标。

Lumbar puncture opening pressure is not a reliable measure of intracranial pressure in children.

作者信息

Cartwright Cathy, Igbaseimokumo Usiakimi

机构信息

Division of Neurosurgery, Children's Mercy Hospital, Kansas City, MO, USA.

Division of Neurosurgery, Children's Mercy Hospital, Kansas City, MO, USA

出版信息

J Child Neurol. 2015 Feb;30(2):170-3. doi: 10.1177/0883073814533006. Epub 2014 May 5.

DOI:10.1177/0883073814533006
PMID:24799366
Abstract

There is very little data correlating lumbar puncture pressures to formal intracranial pressure monitoring despite the widespread use of both procedures. The hypothesis was that lumbar puncture is a single-point measurement and hence it may not be a reliable evaluation of intracranial pressure. The study was therefore carried out to compare lumbar puncture opening pressures with the Camino bolt intracranial pressure monitor in children. Twelve children with a mean age of 8.5 years who had both lumbar puncture and intracranial pressure monitoring were analyzed. The mean lumbar puncture opening pressure was 22.4 mm Hg versus a mean Camino bolt intracranial pressure of 7.8 mm Hg (P < .0001). Lumbar puncture therefore significantly overestimates the intracranial pressure in children. There were no complications from the intracranial pressure monitoring, and the procedure changed the treatment of all 12 children avoiding invasive operative procedures in most of the patients.

摘要

尽管腰椎穿刺和正式的颅内压监测这两种操作都被广泛使用,但将腰椎穿刺压力与正式颅内压监测相关联的数据却非常少。假设是腰椎穿刺是单点测量,因此它可能不是颅内压的可靠评估方法。因此开展了这项研究,以比较儿童腰椎穿刺初压与Camino螺栓颅内压监测结果。分析了12名平均年龄8.5岁、同时进行了腰椎穿刺和颅内压监测的儿童。腰椎穿刺平均初压为22.4毫米汞柱,而Camino螺栓颅内压平均为7.8毫米汞柱(P < .0001)。因此,腰椎穿刺显著高估了儿童的颅内压。颅内压监测没有并发症,该操作改变了所有12名儿童的治疗方案,使大多数患者避免了侵入性手术。

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