Xue You-Qiu, Di Jin-Ming, Luo Yun, Cheng Ke-Jun, Wei Xing, Shi Zhi
Department of Cell Biology & Institute of Biomedicine, College of Life Science and Technology, Jinan University, Guangzhou, Guangdong 510630, China.
Department of Urology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong 510630, China.
Oxid Med Cell Longev. 2014;2014:765832. doi: 10.1155/2014/765832. Epub 2014 Mar 23.
Resveratrol (3,4',5-trihydroxystilbene) is a naturally derived phytoalexin stilbene isolated from grapes and other plants, playing an important role in human health and is well known for its extensive bioactivities, such as antioxidation, anti-inflammatory, anticancer. In addition to resveratrol, scientists also pay attention to resveratrol oligomers, derivatives of resveratrol, which are characterized by the polymerization of two to eight, or even more resveratrol units, and are the largest group of oligomeric stilbenes. Resveratrol oligomers have multiple beneficial properties, of which some are superior in activity, stability, and selectivity compared with resveratrol. The complicated structures and diverse biological activities are of significant interest for drug research and development and may provide promising prospects as cancer preventive and therapeutical agents. This review presents an overview on preventive or anticancer properties of resveratrol oligomers.
白藜芦醇（3,4',5-三羟基茋）是一种从葡萄和其他植物中分离出来的天然植物抗毒素茋，对人体健康起着重要作用，并且以其广泛的生物活性而闻名，如抗氧化、抗炎、抗癌。除了白藜芦醇，科学家们还关注白藜芦醇低聚物，它是白藜芦醇的衍生物，其特征是由两个至八个甚至更多的白藜芦醇单元聚合而成，是最大的一类低聚茋。白藜芦醇低聚物具有多种有益特性，其中一些在活性、稳定性和选择性方面优于白藜芦醇。其复杂的结构和多样的生物活性对药物研发具有重要意义，可能作为癌症预防和治疗药物提供有前景的前景。本文综述了白藜芦醇低聚物的预防或抗癌特性。
