Somatomedin-binding proteins: what role do they play in the growth process?
作者信息
Cianfarani S, Holly J M
机构信息
Department of Paediatrics, Tor Vergata University Medical School, II University of Rome, Italy.
出版信息
Eur J Pediatr. 1989 Nov;149(2):76-9. doi: 10.1007/BF01995850.
PMID:2480240
Abstract
The insulin-like growth factors (IGF-I and IGF-II) circulate bound to specific proteins. Two classes of binding proteins have been relatively well characterized differing in size, immunological activity, and physiological function. This review summarizes the more recent data on IGF-binding proteins, focusing on their possible clinical implications.
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