Finn Maurice, McDonald Skye
a Aged Care Services, Royal North Shore Hospital , University of New South Wales , St Leonards , Australia.
Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2015;22(2):244-58. doi: 10.1080/13825585.2014.915918. Epub 2014 May 12.
The results of a randomized controlled trial of repetition-lag training in older adults with amnestic mild cognitive impairment (aMCI) are reported. A modified repetition-lag training procedure with extended encoding time and strategy choice was used. The training required discriminating studied words from non-studied lures that were repeated at varying intervals during the test phase. Participants were assessed pre/post using untrained measures of cognition and self-report questionnaires. Primary outcome measures were recall of unrelated word pairs both immediately following presentation and following a delay. Secondary outcomes were a measure of attention, cognitive flexibility, and visual working memory. Participants were also asked to report on the frequency of cognitive failures and mood before and after training. Participants (N = 31) were randomized into either the treatment or a no-contact control group and attended the clinic twice per week over a four week period. Twenty-four participants completed the study (twelve in each group). Results indicated that the training group improved at recalling unrelated word pairs after a delay. There were no significant effects of training on other outcomes, self-reported cognitive failures or mood. The results are discussed along with suggestions for future research.
本文报告了一项针对患有遗忘型轻度认知障碍（aMCI）的老年人进行重复滞后训练的随机对照试验结果。采用了一种经过改良的重复滞后训练程序，延长了编码时间并增加了策略选择。该训练要求在测试阶段从非学习过的诱饵中辨别出学习过的单词，这些诱饵会以不同的时间间隔重复出现。使用未经训练的认知测量方法和自我报告问卷对参与者进行训练前/后的评估。主要结局指标是呈现单词对后立即以及延迟后对不相关单词对的回忆。次要结局指标是注意力、认知灵活性和视觉工作记忆的测量。还要求参与者报告训练前后认知失误的频率和情绪。参与者（N = 31）被随机分为治疗组或无接触对照组，并在四周内每周到诊所两次。24名参与者完成了研究（每组12名）。结果表明，训练组在延迟后回忆不相关单词对方面有所改善。训练对其他结局、自我报告的认知失误或情绪没有显著影响。本文对研究结果进行了讨论，并提出了未来研究的建议。
