Chen Chun-Ku, Liang I-Ping, Chang Hsiao-Ting, Chen Wei-Yuan, Chen I-Ming, Wu Mei-Han, Sheu Ming-Huei, Shih Chun-Che
Department of Radiology, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Department of Radiology, Chiayi Branch, Taichung Veterans General Hospital, Chiayi, Taiwan.
J Vasc Surg. 2014 Oct;60(4):937-44. doi: 10.1016/j.jvs.2014.04.008. Epub 2014 May 10.
In this study, we assessed the association between the tortuosity of the thoracic aorta as measured by the reporting standards for thoracic endovascular aortic repair (TEVAR), described by the Society for Vascular Surgery, and midterm outcomes after TEVAR for atherosclerotic aneurysms.
We analyzed 77 consecutive patients who underwent TEVAR for atherosclerotic aneurysms from November 2006 through May 2013 in a single institution. The preoperative aortic tortuosity index (TI) was calculated by computed tomography aortography, and patients were divided into low-tortuosity (TI ≤ 1.29) and high-tortuosity (TI > 1.29) groups. The relationships between TI and the occurrence of endoleaks, complications, and survival were analyzed.
The mean follow-up period was 29 ± 26 months. During this period, endoleaks occurred in 19 patients. Patients in the high-tortuosity group were at greater risk for endoleaks (odds ratio, 9.95; 95% confidence interval, 2.06-48.1; P = .004) and stroke (odds ratio, 13.2; 95% confidence interval, 1.03-169; P = .047) than those in the low-tortuosity group. The overall survival at 1, 3, and 5 years was 73%, 69%, and 63%, respectively, for the high-tortuosity group and 92%, 92%, and 86%, respectively, for the low tortuosity group.
Our findings demonstrated that high tortuosity of the thoracic aorta is associated with higher rates of endoleaks and lower survival in patients undergoing TEVAR for atherosclerotic aneurysms. Patients with aneurysms in a highly tortuous aorta may therefore need greater attention in preoperative planning, perioperative procedures, and follow-up examinations.
在本研究中,我们评估了按照血管外科学会描述的胸主动脉腔内修复术(TEVAR)报告标准所测量的胸主动脉迂曲度与TEVAR治疗动脉粥样硬化性动脉瘤的中期结局之间的关联。
我们分析了2006年11月至2013年5月期间在单一机构接受TEVAR治疗动脉粥样硬化性动脉瘤的77例连续患者。通过计算机断层扫描主动脉造影计算术前主动脉迂曲指数(TI),并将患者分为低迂曲度(TI≤1.29)和高迂曲度(TI>1.29)组。分析TI与内漏发生、并发症及生存之间的关系。
平均随访期为29±26个月。在此期间,19例患者发生内漏。高迂曲度组患者发生内漏(比值比,9.95;95%置信区间,2.06 - 48.1;P = .004)和中风(比值比,13.2;95%置信区间,1.03 - 169;P = .047)的风险高于低迂曲度组。高迂曲度组1年、3年和5年的总生存率分别为73%、69%和63%,低迂曲度组分别为92%、92%和86%。
我们的研究结果表明,胸主动脉高度迂曲与接受TEVAR治疗动脉粥样硬化性动脉瘤的患者内漏发生率较高及生存率较低相关。因此,对于主动脉高度迂曲的动脉瘤患者,在术前规划、围手术期操作及随访检查中可能需要给予更多关注。