多发性硬化症影响量表和多发性硬化症国际生活质量问卷的韩文版有效性。
Validity of korean versions of the multiple sclerosis impact scale and the multiple sclerosis international quality of life questionnaire.
机构信息
Department of Neurology, Kosin University College of Medicine, Busan, Korea.
Biometric Research Branch, Research Institute and Hospital of National Cancer Center, Goyang, Korea.
出版信息
J Clin Neurol. 2014 Apr;10(2):148-56. doi: 10.3988/jcn.2014.10.2.148. Epub 2014 Apr 23.
BACKGROUND AND PURPOSE
Assessment of the health-related quality of life (HRQoL) is important in clinical evaluations of multiple sclerosis (MS) patients for quantifying the impact of illness and treatment on their daily lives. Although MS-specific HRQoL instruments have been used internationally, there are no data regarding HRQoL instruments specifically designed for patients with MS in Korea. The objective of this study was to determine the reliability and validity of the Korean Multiple Sclerosis Impact Scale (MSIS-29) and the Multiple Sclerosis International Quality of Life (MusiQoL) questionnaire.
METHODS
Fifty-six patients with MS were recruited from June 2009 to February 2010 at the National Cancer Center in Korea. The original English versions of the MSIS-29 scale and the MusiQoL questionnaire were translated into Korean and evaluated for their acceptability, reliability, and validity.
RESULTS
The patients wereaged 36.5±8.6 years (mean±SD; range, 20-56 years). Their score on the Expanded Disability Status Scale was 2.0±1.9 (mean; range, 0-7.5), and their disease duration was 5.2±4.7 years (mean±SD; range, 1-24 years). The Korean versions of the MSIS-29 and MusiQoL questionnaires showed satisfactory psychometric properties, including construct validity (item-internal consistencies of 0.59-0.95 and 0.59-0.92, respectively; item-discriminant validities of 95-100% and 93.8-100%), internal consistency (Cronbach's alpha coefficients of 0.96-0.97 and 0.77-0.96), reliability (intraclass correlation coefficients of 0.78-0.90 and 0.50-0.93), unidimensionality (Loevinger scalability coefficients of 0.70-0.78 and 0.63-0.90), and acceptability. External validity testing indicated the presence of significant correlations between similar aspects of the two questionnaires.
CONCLUSIONS
The Korean translated versions of the MSIS-29 and MusiQoL questionnaires demonstrated reliability and validity for measuring HRQoL in Korean patients with MS.
背景与目的
评估多发性硬化症（MS）患者的健康相关生活质量（HRQoL）对于量化疾病和治疗对其日常生活的影响非常重要。尽管国际上已经使用了特定于 MS 的 HRQoL 工具，但韩国尚无专门为 MS 患者设计的 HRQoL 工具的数据。本研究的目的是确定韩国多发性硬化症影响量表（MSIS-29）和多发性硬化症国际生活质量（MusiQoL）问卷的信度和效度。
方法
2009 年 6 月至 2010 年 2 月，在韩国国家癌症中心招募了 56 名 MS 患者。将 MSIS-29 量表和 MusiQoL 问卷的原始英文版本翻译成韩文，并评估其可接受性、信度和效度。
结果
患者年龄为 36.5±8.6 岁（平均值±标准差；范围，20-56 岁）。他们的扩展残疾状况量表评分为 2.0±1.9（平均值；范围，0-7.5），疾病持续时间为 5.2±4.7 年（平均值±标准差；范围，1-24 年）。韩文版 MSIS-29 和 MusiQoL 问卷具有令人满意的心理测量学特性，包括构念效度（项目内部一致性分别为 0.59-0.95 和 0.59-0.92；项目区分效度为 95-100%和 93.8-100%）、内部一致性（克朗巴赫's alpha 系数为 0.96-0.97 和 0.77-0.96）、可靠性（组内相关系数为 0.78-0.90 和 0.50-0.93）、一维性（Loevinger 可度量性系数为 0.70-0.78 和 0.63-0.90）和可接受性。外部有效性测试表明，两个问卷中相似方面之间存在显著相关性。
结论
韩文版 MSIS-29 和 MusiQoL 问卷在测量韩国 MS 患者的 HRQoL 方面具有可靠性和有效性。
Zotero 插件