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Five new terpenoids from the rhizomes of Isodon adenantha.

作者信息

Zhou Xing-Li, Xiao Chao-Jiang, Wu La-Bin, Huang Bo, Dong Xiang, Jiang Bei

机构信息

a College of Pharmacy and Chemistry, Institute of Materia Medica, Dali University , Dali 671000 , China.

出版信息

J Asian Nat Prod Res. 2014;16(6):555-64. doi: 10.1080/10286020.2014.918110. Epub 2014 May 19.

DOI:10.1080/10286020.2014.918110
PMID:24835337
Abstract

Five new terpenoids including 2 labdane diterpenoids (1 and 2), 2 ent-kaurane diterpenoids (3 and 4), and a new oleanane triterpenoid (5), along with 13 known compounds (6-18), were isolated from the ethyl acetate fraction of 70% acetone extract of the rhizomes of Isodonadenantha. Their structures were elucidated based on the analyses of spectroscopic data and comparison of their physicochemical properties. The structure of 1 was further confirmed by single-crystal X-ray diffraction. Cytotoxicity and antibacterial activities of the samples were measured by MTT method and the filter paper disk agar diffusion method. But none of them showed significant activities.

摘要

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