Schuermeyer Joseph, Salomonsen-Sautel Stacy, Price Rumi Kato, Balan Sundari, Thurstone Christian, Min Sung-Joon, Sakai Joseph T
Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO, United States.
Department of Psychiatry, Washington University School of Medicine, St. Louis, MO, United States.
Drug Alcohol Depend. 2014 Jul 1;140:145-55. doi: 10.1016/j.drugalcdep.2014.04.016. Epub 2014 Apr 28.
In 2009, policy changes were accompanied by a rapid increase in the number of medical marijuana cardholders in Colorado. Little published epidemiological work has tracked changes in the state around this time.
Using the National Survey on Drug Use and Health, we tested for temporal changes in marijuana attitudes and marijuana-use-related outcomes in Colorado (2003-11) and differences within-year between Colorado and thirty-four non-medical-marijuana states (NMMS). Using regression analyses, we further tested whether patterns seen in Colorado prior to (2006-8) and during (2009-11) marijuana commercialization differed from patterns in NMMS while controlling for demographics.
Within Colorado those reporting "great-risk" to using marijuana 1-2 times/week dropped significantly in all age groups studied between 2007-8 and 2010-11 (e.g. from 45% to 31% among those 26 years and older; p=0.0006). By 2010-11 past-year marijuana abuse/dependence had become more prevalent in Colorado for 12-17 year olds (5% in Colorado, 3% in NMMS; p=0.03) and 18-25 year olds (9% vs. 5%; p=0.02). Regressions demonstrated significantly greater reductions in perceived risk (12-17 year olds, p=0.005; those 26 years and older, p=0.01), and trend for difference in changes in availability among those 26 years and older and marijuana abuse/dependence among 12-17 year olds in Colorado compared to NMMS in more recent years (2009-11 vs. 2006-8).
Our results show that commercialization of marijuana in Colorado has been associated with lower risk perception. Evidence is suggestive for marijuana abuse/dependence. Analyses including subsequent years 2012+ once available, will help determine whether such changes represent momentary vs. sustained effects.
2009年,政策变化伴随着科罗拉多州医用大麻卡持有者数量的迅速增加。当时很少有已发表的流行病学研究追踪该州的相关变化。
利用全国药物使用和健康调查,我们测试了科罗拉多州(2003 - 2011年)大麻态度和与大麻使用相关结果的时间变化,以及科罗拉多州与34个非医用大麻州(NMMS)在同一年内的差异。通过回归分析,我们进一步测试了在大麻商业化之前(2006 - 2008年)和期间(2009 - 2011年)科罗拉多州出现的模式与NMMS的模式是否不同,同时控制人口统计学因素。
在科罗拉多州,那些报告每周使用大麻1 - 2次“有很大风险”的人在2007 - 2008年至2010 - 2011年期间研究的所有年龄组中显著下降(例如,26岁及以上人群中从45%降至31%;p = 0.0006)。到2010 - 2011年,过去一年大麻滥用/依赖在科罗拉多州12 - 17岁青少年(科罗拉多州为5%,NMMS为3%;p = 0.03)和18 - 25岁青少年(分别为9%和5%;p = 0.02)中变得更为普遍。回归分析表明,与NMMS相比,近年来(2009 - 2011年与2006 - 2008年相比),科罗拉多州12 - 17岁青少年(p = 0.005)和26岁及以上人群(p = 0.01)对大麻风险的认知显著降低,并且26岁及以上人群在大麻可得性变化以及12 - 17岁青少年在大麻滥用/依赖方面存在差异趋势。
我们的结果表明,科罗拉多州大麻商业化与较低的风险认知相关。有证据表明存在大麻滥用/依赖情况。一旦有2012年及以后各年的数据,后续分析将有助于确定这些变化是暂时的还是持续的影响。