Holdsworth Andrew, Bradley Kate, Birch Sally, Browne William J, Barberet Virginie
Radiology Department, University of Bristol Veterinary Hospital, Bristol, BS40 5DU, UK.
Vet Radiol Ultrasound. 2014 Nov-Dec;55(6):620-7. doi: 10.1111/vru.12169. Epub 2014 May 20.
Elastography is a simple, expedient and noninvasive technique that may be used to assess the elasticity or stiffness of a tissue, in conjunction with traditional B-mode ultrasonography. Quantitative assessment of tissue stiffness can be made which involves measurement of the shear wave velocity within the tissue of interest. The goal of this study was to assess the feasibility of elastography for clinical use in the abdomen of conscious small animals and to investigate factors that affect shear wave velocity measurement. Elastography was performed on the liver, spleen, and kidneys of 15 dogs at predefined depths within the parenchyma. Breed, age, gender, neuter status, and weight were documented for each animal. Depth at which measurements were taken had a significant negative relationship with the shear wave velocity value obtained. Individual dog effects, such as weight and gender, also appeared to have a significant effect on the shear wave velocity measurement for specific organs; weight had a significant positive effect on the shear wave velocity for each of the organs examined, whereas the effect of gender was inconsistent between organs (having a positive effect for the liver and a negative effect for the spleen). It is hoped that these results may act as a baseline to guide further work into the field of elastography in companion animals.
弹性成像技术是一种简单、便捷且无创的技术，可结合传统B型超声用于评估组织的弹性或硬度。可以对组织硬度进行定量评估，这涉及到测量感兴趣组织内的剪切波速度。本研究的目的是评估弹性成像技术在清醒小动物腹部临床应用的可行性，并研究影响剪切波速度测量的因素。在15只犬的肝脏、脾脏和肾脏的实质内预定义深度处进行弹性成像检查。记录每只动物的品种、年龄、性别、绝育状态和体重。测量深度与获得的剪切波速度值呈显著负相关。个体犬的因素，如体重和性别，似乎也对特定器官的剪切波速度测量有显著影响；体重对每个检查器官的剪切波速度有显著正影响，而性别对不同器官的影响不一致（对肝脏有正影响，对脾脏有负影响）。希望这些结果可作为基线，为伴侣动物弹性成像领域的进一步研究提供指导。
