Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.
Pharmacognosy Department, Faculty of Pharmacy, Mansoura University, 35516, Egypt.
Chin J Nat Med. 2014 May;12(5):345-50. doi: 10.1016/S1875-5364(14)60042-X.
One of the leading causes of death worldwide is cardiovascular disease, hence searching for a cure is an important endeavor. The totally safe, edible, and inexpensive Boswellia plant exudate, known as olibanum or frankincense, is considered to possess diverse medicinal values in traditional medicine and from recent biological studies. Investigating the cardioprotective and antioxidant activities of olibanum from a Boswellia species, family Bursearaceae, namely Boswellia carteri Birdw. was the aim of this study. Cardioprotective activity was evaluated using a model of myocardial infarction induced by isoprenaline (ISO), while antioxidant activity was tested adopting nitric oxide scavenging (NOS) and azino-bis-3-ethyl benzthiazoline-6-sulfonic acid (ABTS) assays. The results revealed a mild cardioprotective effect and weak antioxidant activity.
全球主要死亡原因之一是心血管疾病,因此寻找治疗方法是一项重要的努力。完全安全、可食用且廉价的 Boswellia 植物渗出物,称为乳香或没药,被认为在传统医学和最近的生物学研究中具有多种药用价值。本研究旨在研究来自 Bursearaceae 科 Boswellia 属的 Boswellia carteri Birdw. 的乳香的心脏保护和抗氧化活性。使用异丙肾上腺素 (ISO) 诱导的心肌梗死模型评估心脏保护活性,同时采用一氧化氮清除 (NOS) 和氮蓝四唑 (ABTS) 测定法测试抗氧化活性。结果表明具有轻度的心脏保护作用和较弱的抗氧化活性。