Hum Reprod. 2014 Jul;29(7):1353-9. doi: 10.1093/humrep/deu111. Epub 2014 May 23.
This Task Force document explores the ethical issues involved in the debate about the scope of genetic screening of gamete donors. Calls for expanded donor screening arise against the background of both occasional findings of serious but rare genetic conditions in donors or donor offspring that were not detected through present screening procedures and the advent of new genomic technologies promising affordable testing of donors for a wide range of conditions. Ethical principles require that all stakeholders' interests are taken into account, including those of candidate donors. The message of the profession should be that avoiding all risks is impossible and that testing should remain proportional.
本专家组文件探讨了配子供体基因筛查范围争议所涉及的伦理问题。扩大供体筛查的呼声一方面源于当前筛查程序未能检测到供体或供体后代中偶尔出现的严重但罕见的遗传疾病，另一方面也源于新的基因组技术有望以可负担的价格对供体的多种疾病进行检测。伦理原则要求考虑所有利益相关者的利益，包括候选供体的利益。该行业的信息应该是，避免所有风险是不可能的，检测应保持适度。
