Diamond Eli L, Corner Geoffrey W, De Rosa Antonio, Breitbart William, Applebaum Allison J
Department of Neurology, Memorial Sloan-Kettering Cancer Center, 1275 York Avenue, Box 52, New York, NY, 10065, USA,
J Neurooncol. 2014 Sep;119(2):227-34. doi: 10.1007/s11060-014-1487-1. Epub 2014 May 30.
Malignant glioma (MG) is a devastating neurological disease with a uniformly poor prognosis and a clinical course characterized by progressive functional and cognitive impairment. A small body of literature addresses patients' and caregivers' prognostic awareness (PA), or understanding of prognosis in patients with cancer. Studies that examine PA and desire for prognostic information among patients with MG are limited. We sought to review the existing literature on PA and communication of prognostic information to patients with MG. Fourteen studies examining PA or experience and preferences regarding communication of prognostic information were included. The definition and measurement of PA across studies varied, and the prevalence of accurate PA ranged from 25 to 100 % of participants. There is likely a subset of patients who do not desire accurate prognostic information, although the patient and disease characteristics that predict this preference are currently unknown. This review suggests that patients with MG desire prognostic information communicated in a manner that preserves hope. Systematic investigation to define communication needs for prognostic information in the unique clinical setting of MG is needed.
恶性胶质瘤（MG）是一种毁灭性的神经系统疾病，预后普遍较差，临床病程以进行性功能和认知障碍为特征。一小部分文献探讨了患者及其护理人员的预后意识（PA），即对癌症患者预后的理解。研究MG患者的PA以及对预后信息的需求的研究有限。我们试图回顾关于MG患者PA以及预后信息沟通的现有文献。纳入了14项研究PA或关于预后信息沟通的经验及偏好的研究。各研究中PA的定义和测量方法各不相同，准确PA的患病率在参与者的25%至100%之间。可能有一部分患者不希望获得准确的预后信息，尽管目前尚不清楚预测这种偏好的患者和疾病特征。本综述表明，MG患者希望以保留希望的方式传达预后信息。需要进行系统研究，以确定MG独特临床环境中预后信息的沟通需求。
