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持续血糖监测的当前趋势

Current Trends in Continuous Glucose Monitoring.

作者信息

Lodwig Volker, Kulzer Bernhard, Schnell Oliver, Heinemann Lutz

机构信息

Roche Diagnostics, Mannheim, Germany.

Diabetesklinik Bad Mergentheim, Bad Mergentheim, Germany.

出版信息

J Diabetes Sci Technol. 2014 Mar;8(2):390-396. doi: 10.1177/1932296814525826. Epub 2014 Mar 13.

DOI:10.1177/1932296814525826
PMID:24876592
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4455393/
Abstract

The market introduction of systems for continuous glucose monitoring (CGM) some 15 years ago did not immediately revolutionize the treatment of diabetes; however, for a given group of patients, it would almost be inconceivable nowadays to imagine life without CGM. One day the development of insulin pumps together with CGM could culminate in an artificial pancreas system. The performance of the glucose sensors used for glucose measurement in the interstitial fluid in the subcutaneous tissue and the algorithms employed to analyze these data have improved so much over the past decade that current CGM systems by far outperform those of the first generations. This commentary discusses a number of aspects about what we have learned since CGM systems entered the market and what current trends exist in their usage. Some of these are major hurdles facing a more widespread usage of CGM.

摘要

大约15年前,连续血糖监测(CGM)系统进入市场时,并没有立即给糖尿病治疗带来变革;然而,对于特定的一群患者来说,如今很难想象没有CGM的生活会是什么样。总有一天,胰岛素泵与CGM的发展可能会促成人工胰腺系统的出现。在过去十年里,用于测量皮下组织间质液中葡萄糖的葡萄糖传感器的性能以及用于分析这些数据的算法都有了很大改进,以至于目前的CGM系统远比第一代系统性能优越。本评论讨论了自CGM系统进入市场以来我们所学到的一些方面,以及其当前的使用趋势。其中一些是CGM更广泛使用面临的主要障碍。

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本文引用的文献

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ASPIRE In-Home: rationale, design, and methods of a study to evaluate the safety and efficacy of automatic insulin suspension for nocturnal hypoglycemia.ASPIRE居家研究:一项评估自动胰岛素暂停预防夜间低血糖安全性和有效性的研究的基本原理、设计与方法
J Diabetes Sci Technol. 2013 Jul 1;7(4):1005-10. doi: 10.1177/193229681300700424.
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Performance evaluation of three continuous glucose monitoring systems: comparison of six sensors per subject in parallel.三种连续血糖监测系统的性能评估:每位受试者并行比较六个传感器
J Diabetes Sci Technol. 2013 Jul 1;7(4):842-53. doi: 10.1177/193229681300700406.
3
Performance evaluations of continuous glucose monitoring systems: precision absolute relative deviation is part of the assessment.连续血糖监测系统的性能评估:精确绝对相对偏差是评估的一部分。
J Diabetes Sci Technol. 2013 Jul 1;7(4):824-32. doi: 10.1177/193229681300700404.
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Threshold-based insulin-pump interruption for reduction of hypoglycemia.基于阈值的胰岛素泵中断以减少低血糖。
N Engl J Med. 2013 Jul 18;369(3):224-32. doi: 10.1056/NEJMoa1303576. Epub 2013 Jun 22.
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Accuracy and reliability of continuous glucose monitoring systems: a head-to-head comparison.连续血糖监测系统的准确性和可靠性:头对头比较。
Diabetes Technol Ther. 2013 Aug;15(8):722-7. doi: 10.1089/dia.2013.0049. Epub 2013 May 7.
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