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一项关于意大利医生对干细胞研究看法的调查:医生们的偏好与法律要求

A survey of Italian physicians' opinion about stem cells research: what doctors prefer and what the law requires.

作者信息

Frati Paola, Gulino Matteo, Pacchiarotti Arianna, D'Errico Stefano, Sicuro Lorella, Fineschi Vittorio

机构信息

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, University of Rome La Sapienza, Viale Regina Elena 336, 00161 Rome, Italy ; Istituto Neurologico Mediterraneo, Neuromed, IRCCS, 86170 Isernia, Italy.

Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, University of Rome La Sapienza, Viale Regina Elena 336, 00161 Rome, Italy.

出版信息

Biomed Res Int. 2014;2014:480304. doi: 10.1155/2014/480304. Epub 2014 Apr 30.

Abstract

To evaluate the Italian physicians' knowledge/information level about the therapeutic potential of stem cells, the research choice between embryonic and cordonal stem cells, and the preference between autologous and heterologous storage of cordonal stem cells, we performed a national survey. The questionnaire--distributed to 3361 physicians--involved physicians of different religious orientations and of different medical specialities. Most of the physicians involved (67%) were Catholics, and the majority were gynaecologists and paediatricians (43%) who are mainly in charge to inform future mothers about the possibility of cordonal stem cells conservation. The majority of the physicians interviewed do not have specific knowledge about stem cells (59%), most of them having only generic information (92%). The largest part of physicians prefer to use umbilical cord blood cells rather than embryonic stem cells. Nevertheless, a large percentage of physicians were in favour of embryo research, especially when embryos are supernumerary (44% versus 34%). Eighty-seven % of the physicians interviewed proved to have a general knowledge about stem cells and believe in their therapeutic potential. They prefer research on cordonal stem cells rather than on embryo stem cells. Although they are in favour of heterologous stem cells donation, they still prefer cryopreservation for personal use.

摘要

为评估意大利医生关于干细胞治疗潜力的知识/信息水平、胚胎干细胞与脐带血干细胞之间的研究选择,以及脐带血干细胞自体储存与异体储存之间的偏好,我们开展了一项全国性调查。该问卷发放给了3361名医生,涉及不同宗教信仰和不同医学专业的医生。参与调查的大多数医生(67%)是天主教徒,且多数是妇科医生和儿科医生(43%),他们主要负责向未来的母亲告知保存脐带血干细胞的可能性。大多数接受访谈的医生对干细胞没有专业知识(59%),其中大多数人只有一般性信息(92%)。大部分医生更倾向于使用脐带血细胞而非胚胎干细胞。然而,很大比例的医生支持胚胎研究,尤其是多余胚胎的研究(44%对34%)。87%接受访谈的医生表明对干细胞有基本了解并相信其治疗潜力。他们更倾向于对脐带血干细胞而非胚胎干细胞进行研究。尽管他们支持异体干细胞捐赠,但仍更倾向于自体冷冻保存。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b191/4022064/12db1a5ad4d4/BMRI2014-480304.001.jpg

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