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与替加环素相关的急性泛发性脓疱性皮病

Acute generalized exanthematous pustulosis associated with tigecycline.

作者信息

Ozturk Savas, Ustun Cemal, Pehlivan Sultan, Ucak Haydar

机构信息

Department of Dermatology, Balikesir University Medical Faculty, Balikesir, Turkey.

Department of Infectious Diseases and Clinical Microbiology, Ministry of Health Elazig Education and Research Hospital, Elazig, Turkey.

出版信息

Ann Dermatol. 2014 Apr;26(2):246-9. doi: 10.5021/ad.2014.26.2.246. Epub 2014 Apr 30.

Abstract

Acute generalized exanthematous pustulosis (AGEP) is a severe and rare eruption that develops mostly from factors related to drugs. It is characterized by a fever and a pustular eruption on the erythematous skin with an acute onset and without follicular localization. Etiopathogenesis has not yet been fully explained. Although it is similar to pustular psoriasis, its clinical, historical and histopathological characteristics are different. In this article, we present a case of AGEP associated with tigecycline that developed in a patient followed up in the intensive care unit for three months with an intra-abdominal injury after a trauma and Acinetobacter baumannii infection.

摘要

急性泛发性脓疱性皮病(AGEP)是一种严重且罕见的皮疹,主要由药物相关因素引起。其特征为发热以及在红斑皮肤上出现脓疱疹,起病急,无毛囊性分布。病因发病机制尚未完全阐明。尽管它与脓疱型银屑病相似,但其临床、病史及组织病理学特征有所不同。在本文中,我们报告了一例与替加环素相关的AGEP病例,该病例发生在一名因外伤导致腹部损伤并感染鲍曼不动杆菌后,在重症监护病房接受了三个月随访的患者身上。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a910/4037680/87a81f50e76d/ad-26-246-g001.jpg

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