Yung Edward, Trubnik Valerie, Katz L Jay
Department of Ophthalmology, SUNY Stony Brook, 33 Research Way, East Setauket, NY, 11733, USA,
Graefes Arch Clin Exp Ophthalmol. 2014 Aug;252(8):1179-88. doi: 10.1007/s00417-014-2668-5. Epub 2014 May 29.
To review the existing technology for self-tonometry and evaluate methods for continuous monitoring of IOP currently undergoing development and clinical trials in humans.
Glaucoma is one of the leading causes of blindness worldwide. Current glaucoma therapy is focused primarily on lowering intraocular pressures (IOP). Decisions to modify treatment regiments are primarily based on office IOP. Since IOP fluctuates throughout the day, values obtained in the office may be a poor representation of the patient's disease. IOP measurements outside of the physician's office environment would provide better knowledge of the disease state and allow for better-informed medical decision making.
We performed a literature search using Medline and IEEE database for studies investigating technologies that have been developed for continuous 24-hour IOP monitoring.
There is currently no technology that has been approved for use to allow for continuous monitoring of IOP fluctuations. New experimental technology being developed and currently undergoing clinical trials has demonstrated potential for changing the diagnosis and management of glaucoma.
回顾现有的眼压自测量技术,并评估目前正在人类中进行开发和临床试验的眼压连续监测方法。
青光眼是全球主要致盲原因之一。当前青光眼治疗主要集中在降低眼压(IOP)。调整治疗方案的决策主要基于诊室眼压。由于眼压在一天中会波动,在诊室获得的值可能无法很好地反映患者的病情。在医生诊室环境之外进行眼压测量将能更好地了解疾病状态,并有助于做出更明智的医疗决策。
我们使用Medline和IEEE数据库进行文献检索,以查找研究已开发的用于24小时眼压连续监测技术的研究。
目前尚无已获批用于连续监测眼压波动的技术。正在开发且目前正在进行临床试验的新实验技术已显示出改变青光眼诊断和管理的潜力。