• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

粒子放射外科:医学物理学的一个新前沿。

Particle radiosurgery: a new frontier of physics in medicine.

作者信息

Bert Christoph, Durante Marco

机构信息

Friedrich-Alexander University Erlangen-Nürnberg and University Hospital Erlangen, Germany; GSI Helmholtz Centre for Heavy Ion Research, Darmstadt, Germany.

GSI Helmholtz Centre for Heavy Ion Research, Darmstadt, Germany; Technical University Darmstadt, Germany.

出版信息

Phys Med. 2014 Jul;30(5):535-8. doi: 10.1016/j.ejmp.2014.04.011. Epub 2014 Jun 2.

DOI:10.1016/j.ejmp.2014.04.011
PMID:24889154
Abstract

Radiosurgery was introduced over half a century ago for treatment of intracranial lesions. In more recent years, stereotactic radiotherapy has rapidly advanced and is now commonly used for treatments of both cranial and extracranial lesions with high doses delivered in a few, down to a single fraction. The results of a workshop on Particle radiosurgery: A new frontier of physics in medicine held at Obergurgl, Austria during August 25-29 2013 are summarized in this issue with an overview presented in this paper. The focus was laid on particle radiosurgery but the content also includes current practice in x-ray radiosurgery and the overarching research in radiobiology and motion management for extracranial lesions. The results and discussions showed that especially research in radiobiology of high-dose charged-particles and motion management are necessary for the success of particle radiosurgery.

摘要

放射外科手术在半个多世纪前就已被引入用于治疗颅内病变。近年来,立体定向放射治疗发展迅速,如今常用于治疗颅内和颅外病变,高剂量可在几次分割甚至单次分割内给予。本期总结了2013年8月25日至29日在奥地利奥贝古格尔举行的“粒子放射外科手术:医学物理的新前沿”研讨会的结果,并在本文中进行了概述。重点是粒子放射外科手术,但内容还包括X射线放射外科手术的当前实践以及颅外病变放射生物学和运动管理的总体研究。结果和讨论表明,对于粒子放射外科手术的成功而言,高剂量带电粒子放射生物学和运动管理方面的研究尤其必要。

相似文献

1
Particle radiosurgery: a new frontier of physics in medicine.粒子放射外科:医学物理学的一个新前沿。
Phys Med. 2014 Jul;30(5):535-8. doi: 10.1016/j.ejmp.2014.04.011. Epub 2014 Jun 2.
2
Regarding: Rosenthal DI, Glatstein E. "We've Got a Treatment, but What's the Disease?" The Oncologist 1996;1.关于:罗森塔尔·迪、格拉茨坦·埃。《我们有了一种治疗方法,但疾病是什么?》,《肿瘤学家》1996年;第1期。
Oncologist. 1997;2(1):59-61.
3
[Recent developments in radiation oncology-integrating radiation physics and molecular radiobiology advances into clinical radiotherapy practice and beyond].[放射肿瘤学的最新进展——将放射物理学和分子放射生物学进展融入临床放射治疗实践及其他领域]
Ai Zheng. 2008 Aug;27(8):885-93.
4
Charged-particle radiosurgery for intracranial vascular malformations.颅内血管畸形的带电粒子放射外科治疗。
Neurosurg Clin N Am. 1992 Jan;3(1):99-139.
5
We've Got a Treatment, but What's the Disease? Or A Brief History of Hypofractionation and Its Relationship to Stereotactic Radiosurgery.我们有了一种治疗方法,但疾病是什么?或短程放疗简史及其与立体定向放射外科的关系。
Oncologist. 1996;1(1 & 2):1-7.
6
The radiobiology of radiosurgery and stereotactic radiotherapy.立体定向放射外科和立体定向放射治疗的放射生物学
Med Dosim. 1998 Fall;23(3):201-7. doi: 10.1016/s0958-3947(98)00010-7.
7
Principles of radiobiology of stereotactic radiosurgery and clinical applications in the central nervous system.立体定向放射外科的放射生物学原理及其在中枢神经系统的临床应用。
Technol Cancer Res Treat. 2012 Feb;11(1):3-13. doi: 10.7785/tcrt.2012.500229.
8
The radiobiological and physical basis for radiotherapy with protons and heavier ions.质子和重离子放射治疗的放射生物学和物理学基础。
Strahlenther Onkol. 1990 Jan;166(1):10-3.
9
Radiation therapy with charged particles.带电粒子放射治疗。
Semin Radiat Oncol. 2006 Oct;16(4):249-59. doi: 10.1016/j.semradonc.2006.04.008.
10
The radiobiology of hypofractionation.大分割放疗的放射生物学
Clin Oncol (R Coll Radiol). 2015 May;27(5):260-9. doi: 10.1016/j.clon.2015.02.001. Epub 2015 Mar 18.

引用本文的文献

1
Particle Beam Radiobiology Status and Challenges: A PTCOG Radiobiology Subcommittee Report.粒子束放射生物学现状与挑战:国际粒子治疗协作组放射生物学小组委员会报告
Int J Part Ther. 2024 Aug 8;13:100626. doi: 10.1016/j.ijpt.2024.100626. eCollection 2024 Sep.
2
Biological Cardiac Tissue Effects of High-Energy Heavy Ions - Investigation for Myocardial Ablation.高能重离子对生物心脏组织的影响 - 心肌消融的研究。
Sci Rep. 2019 Mar 21;9(1):5000. doi: 10.1038/s41598-019-41314-x.
3
A meta-analysis of the abscopal effect in preclinical models: Is the biologically effective dose a relevant physical trigger?
临床前模型中远隔效应的荟萃分析:生物学有效剂量是相关的物理触发因素吗?
PLoS One. 2017 Feb 21;12(2):e0171559. doi: 10.1371/journal.pone.0171559. eCollection 2017.
4
Particle therapy of moving targets-the strategies for tumour motion monitoring and moving targets irradiation.移动靶标的粒子治疗——肿瘤运动监测与移动靶标照射策略
Br J Radiol. 2016 Oct;89(1066):20150275. doi: 10.1259/bjr.20150275. Epub 2016 Jul 19.
5
Modeling Combined Chemotherapy and Particle Therapy for Locally Advanced Pancreatic Cancer.局部晚期胰腺癌联合化疗与粒子治疗的建模
Front Oncol. 2015 Jul 6;5:145. doi: 10.3389/fonc.2015.00145. eCollection 2015.