Radcliff Kristen E, Kepler Christopher K, Maaieh Motasem, Anderson D Greg, Rihn Jeffrey, Albert Todd, Vaccaro Alex, Hilibrand Alan
Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, PA, USA.
Orthop Surg. 2014 May;6(2):118-20. doi: 10.1111/os.12103.
Adjacent segment disease (ASD) requiring treatment or re-operation is a common problem after surgery on the lumbar spine. The hypothesis of this retrospective study was that ASD occurs less often following lumbar spine fusion in patients who undergo percutaneous minimally invasive (MIS) instrumentation than in those in whom open instrumentation is used.
A case-control study was performed on consecutive patients who had undergone staged single or two level anterior lumbar interbody fusion for degenerative conditions followed by open or MIS instrumentation from 2002 to 2005 in our institution. ASD was defined as that necessitating additional procedures for new symptoms related to an adjacent lumbar dermatome.
One hundred and seventeen patients met the inclusion criteria. Of these, 53 had been followed up by chart or medical record review for longer than one year. There were 23 patients in the MIS group and 30 in the open group. Of the 30 patients in the open group, 9 had developed ASD (30%). Of the 23 patients in the MIS group, 7 had developed ASD (30%). This difference is not statistically significant (P = 1.00).
Contrary to our hypothesis, there was no significant difference in incidence of ASD in patients who had underwent open versus percutaneous instrumentation following anterior lumbar interbody fusion.
需要治疗或再次手术的相邻节段疾病(ASD)是腰椎手术后的常见问题。这项回顾性研究的假设是,与采用开放内固定的患者相比,接受经皮微创(MIS)内固定的患者在腰椎融合术后发生ASD的情况较少。
对2002年至2005年在我院因退行性疾病接受分期单节段或双节段前路腰椎椎间融合术,随后采用开放或MIS内固定的连续患者进行病例对照研究。ASD被定义为因相邻腰椎皮节出现新症状而需要额外手术的情况。
117例患者符合纳入标准。其中,53例通过病历或医疗记录回顾进行了超过一年的随访。MIS组有23例患者,开放组有30例患者。开放组的30例患者中,9例发生了ASD(30%)。MIS组的23例患者中,7例发生了ASD(30%)。这种差异无统计学意义(P = 1.00)。
与我们的假设相反,前路腰椎椎间融合术后采用开放或经皮内固定的患者中,ASD的发生率没有显著差异。