Al-Mammari Said, Selvarajah Uma, East James E, Bailey Adam A, Braden Barbara
Translational Gastroenterology Unit, Oxford University Hospitals, Oxford, UK.
Translational Gastroenterology Unit, Oxford University Hospitals, Oxford, UK.
Dig Liver Dis. 2014 Aug;46(8):716-9. doi: 10.1016/j.dld.2014.05.001. Epub 2014 Jun 2.
Proximal esophageal heterotopic gastric mucosa or so-called inlet patch in the cervical oesophagus is easily missed on endoscopic examination because of its localisation, usually just below the upper oesophageal sphincter. We evaluated the clinical use of narrow band imaging for detection of inlet patches.
In this prospective, controlled observational study, 1407 subsequent patients underwent oesophagogastroduodenoscopy with or without narrow band imaging on withdrawal of the endoscope in the cervical oesophagus.
One endoscopist who was not aware of the prospective observation documented 6 (1.17%) cases of inlet patches in 515 oesophagogastroduodenoscopies compared to 4 cases out of 382 (1.05%) performed by the endoscopist who paid special attention to the presence of inlet patches but did not routinely apply narrow band imaging (OR 0.89, CI 95% 0.25-3.20, p=0.85). In comparison, 17 cases of inlet patches out of 510 (3.33%) were detected by the endoscopist who routinely applied narrow band imaging. The detection rate of proximal oesophageal heterotopic gastric mucosa using narrow band imaging was significantly higher compared to white light endoscopy only (OR 3.06, CI 95% 1.39-6.73, p=0.005).
Withdrawal of the endoscope from the cervical oesophagus using narrow band imaging increased the detection of inlet patches about three-fold compared to standard white light endoscopy.
近端食管异位胃黏膜,即所谓的位于颈段食管的入口斑,由于其位置通常就在食管上括约肌下方,在内镜检查时很容易被漏诊。我们评估了窄带成像在检测入口斑方面的临床应用。
在这项前瞻性对照观察研究中,1407例患者在颈段食管退镜时接受了常规或联合窄带成像的食管胃十二指肠镜检查。
一位不了解前瞻性观察的内镜医师在515例食管胃十二指肠镜检查中记录到6例(1.17%)入口斑,而一位特别留意入口斑存在但未常规应用窄带成像的内镜医师在382例检查中发现了4例(1.05%)(比值比0.89,95%置信区间0.25 - 3.20,p = 0.85)。相比之下,一位常规应用窄带成像的内镜医师在510例检查中发现了17例(3.33%)入口斑。与仅使用白光内镜相比,使用窄带成像检测近端食管异位胃黏膜的检出率显著更高(比值比3.06,95%置信区间1.39 - 6.73,p = 0.005)。
与标准白光内镜相比,在颈段食管退镜时使用窄带成像可使入口斑的检出率提高约三倍。