金和银纳米颗粒在生物诊断、治疗及药物递送方面的光学、光热和易调控的表面化学性质。
The optical, photothermal, and facile surface chemical properties of gold and silver nanoparticles in biodiagnostics, therapy, and drug delivery.
作者信息
Austin Lauren A, Mackey Megan A, Dreaden Erik C, El-Sayed Mostafa A
机构信息
Laser Dynamics Laboratory, Department of Chemistry and Biochemistry, Georgia Institute of Technology, 901 Atlantic Dr. NW, Atlanta, GA, 30332-0400, USA.
出版信息
Arch Toxicol. 2014 Jul;88(7):1391-417. doi: 10.1007/s00204-014-1245-3. Epub 2014 Jun 4.
Abstract
Nanotechnology is a rapidly growing area of research in part due to its integration into many biomedical applications. Within nanotechnology, gold and silver nanostructures are some of the most heavily utilized nanomaterial due to their unique optical, photothermal, and facile surface chemical properties. In this review, common colloid synthesis methods and biofunctionalization strategies of gold and silver nanostructures are highlighted. Their unique properties are also discussed in terms of their use in biodiagnostic, imaging, therapeutic, and drug delivery applications. Furthermore, relevant clinical applications utilizing gold and silver nanostructures are also presented. We also provide a table with reviews covering related topics.
摘要
纳米技术是一个快速发展的研究领域，部分原因是它已融入许多生物医学应用之中。在纳米技术领域，金和银纳米结构因其独特的光学、光热和表面化学性质，成为应用最为广泛的纳米材料。本综述重点介绍了金和银纳米结构的常见胶体合成方法及生物功能化策略。还讨论了它们在生物诊断、成像、治疗和药物递送应用中的独特性质。此外，还介绍了利用金和银纳米结构的相关临床应用。我们还提供了一个涵盖相关主题综述的表格。
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