Psychiatry Clin Neurosci. 2014 Mar;68(3):176-81. doi: 10.1111/pcn.12102.
The aim of this study was to investigate the association between subjective memory complaints (SMC) and sex.
We researched the prevalence of SMC in a sample of 394 participants who were at least 60 years of age (138 male and 256 female). We also administered the Mini-Mental State Examination (MMSE) and the Center for Epidemiologic Studies for Depression (CES-D) scale. A multiple logistic regression analysis, which included SMC in association with the MMSE or CES-D scores and other confounding factors, was performed to determine the influence of sex on SMC. A P-value < 0.05 was considered statistically significant.
The durations of education of male participants were significantly higher than those of female participants. MMSE scores for female participants were significantly higher than those for male participants. There was no significant difference in CES-D scores between male and female participants. Twenty-four male participants and 72 female participants showed evidence of SMC. The incidence of SMC was more frequent in female participants than in male participants. In all participants, sex difference and CES-D score were significantly associated with SMC. In male participants, MMSE score was independently and significantly associated with SMC. Both in female participants and all participants, CES-D score was independently and significantly associated with SMC.
SMC varied by sex and were associated with the degree of cognitive impairment in male participants, while they were associated with depressive symptoms in female participants.
本研究旨在探讨主观记忆抱怨（SMC）与性别之间的关联。
我们研究了至少 60 岁的 394 名参与者中 SMC 的患病率（138 名男性和 256 名女性）。我们还进行了简易精神状态检查（MMSE）和抑郁流行病学研究中心量表（CES-D）评估。进行了多变量逻辑回归分析，将 SMC 与 MMSE 或 CES-D 评分及其他混杂因素相关联，以确定性别对 SMC 的影响。P 值<0.05 被认为具有统计学意义。
男性参与者的受教育时间明显长于女性参与者。女性参与者的 MMSE 评分明显高于男性参与者。男性和女性参与者的 CES-D 评分无显著差异。24 名男性参与者和 72 名女性参与者出现 SMC 迹象。女性参与者的 SMC 发生率明显高于男性参与者。在所有参与者中，性别差异和 CES-D 评分与 SMC 显著相关。在男性参与者中，MMSE 评分与 SMC 独立且显著相关。在女性参与者和所有参与者中，CES-D 评分与 SMC 独立且显著相关。
SMC 因性别而异，与男性参与者认知障碍程度相关，而与女性参与者的抑郁症状相关。
