利福平：一种具有脑保护功能的抗生素。
RIFAMPICIN: an antibiotic with brain protective function.
作者信息
Yulug Burak, Hanoglu Lütfü, Kilic Ertugrul, Schabitz Wolf Rüdiger
机构信息
Department of Neurology, University of Istanbul-Medipol, Istanbul, Turkey.
Department of Neurology, University of Istanbul-Medipol, Istanbul, Turkey.
出版信息
Brain Res Bull. 2014 Aug;107:37-42. doi: 10.1016/j.brainresbull.2014.05.007. Epub 2014 Jun 4.
Abstract
Besides its well known antibiotic activity rifampicin exerts multiple brain protective functions in acute cerebral ischemia and chronic neurodegeneration. The present mini-review gives an update of the unique activity of rifampicin in different diseases including Parkinson's disease, meningitis, stroke, Alzheimer's disease and optic nerve injury.
摘要
除了其广为人知的抗生素活性外，利福平在急性脑缺血和慢性神经退行性变中发挥多种脑保护功能。本综述简要介绍了利福平在帕金森病、脑膜炎、中风、阿尔茨海默病和视神经损伤等不同疾病中的独特活性。
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