Croft Lindsay, Sorkin John, Gallicchio Lisa
Department of Epidemiology and Public Health, University of Maryland, Baltimore, Baltimore, MD, USA.
Support Care Cancer. 2014 Nov;22(11):3027-34. doi: 10.1007/s00520-014-2308-y. Epub 2014 Jun 8.
There are an increasing number of breast cancer survivors, but their psychosocial and supportive care needs are not well-understood. Recent work has found marital status, social support, and optimism to be associated with quality of life, but little research has been conducted to understand how these factors relate to one another.
Survey data from 722 breast cancer survivors were analyzed to estimate the association between marital status and optimism score, as measured using the Life Orientation Test-Revised. Linear regression was used to estimate the relationship of marital status and optimism, controlling for potential confounding variables and assessing effect modification.
The results showed that the association between marital status and optimism was modified by time since breast cancer diagnosis. Specifically, in those most recently diagnosed (within 5 years), married breast cancer survivors had a 1.50 higher mean optimism score than unmarried survivors (95 % confidence interval (CI) 0.37, 2.62; p = 0.009). The difference in optimism score by marital status was not present more than 5 years from breast cancer diagnosis.
Findings suggest that among breast cancer survivors within 5 years since diagnosis, those who are married have higher optimism scores than their unmarried counterparts; this association was not observed among longer-term breast cancer survivors. Future research should examine whether the difference in optimism score among this subgroup of breast cancer survivors is clinically relevant.
乳腺癌幸存者的数量日益增加,但其心理社会和支持性护理需求尚未得到充分了解。近期研究发现婚姻状况、社会支持和乐观情绪与生活质量相关,但对于这些因素之间如何相互关联的研究较少。
分析了722名乳腺癌幸存者的调查数据,以评估婚姻状况与使用修订版生活取向测试所测量的乐观得分之间的关联。采用线性回归来估计婚姻状况与乐观情绪之间的关系,控制潜在的混杂变量并评估效应修正。
结果显示,婚姻状况与乐观情绪之间的关联因乳腺癌诊断后的时间而有所改变。具体而言,在最近诊断的患者(5年内)中,已婚乳腺癌幸存者的平均乐观得分比未婚幸存者高1.50(95%置信区间(CI) 0.37, 2.62;p = 0.009)。乳腺癌诊断超过5年后,婚姻状况导致的乐观得分差异不存在。
研究结果表明,在诊断后5年内的乳腺癌幸存者中,已婚者的乐观得分高于未婚者;在长期乳腺癌幸存者中未观察到这种关联。未来的研究应探讨这一亚组乳腺癌幸存者中乐观得分差异是否具有临床相关性。