Tabatabaee Masumeh Hasani, Arami Sakineh, Ghavam Maryam, Rezaii Asieh
Associate Professor, Dental Research Center Dentistry Research Institute, Department of Operative Dentistry, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran.
Assistant Professor, Department of Operative Dentistry, School of Dentistry Tehran University of Medical Sciences, Tehran, Iran.
J Dent (Tehran). 2014 Jan;11(1):56-66. Epub 2014 Jan 31.
The aim of this study was to assess the effect of bleaching on elution of monomers from nanofilled and microhybrid composites.
80 samples (5mm diameter and 3mm thickness) of each composite were prepared. After curing, half of them were randomly polished. Each group was divided into 8 subgroups and immersed in water or 10%, 20% and 30% H2O2 for 3 or 8 hours. Eluted Bis-GMA (Bis-phenol A Glycidyl Dimethacrylate), TEGDMA (Triethyleneglycol Dimethacrylate), UDMA (Urethane Dimethacrylate) and BisEMA (Bis-phenol A ethoxylate Dimethacrylate) were quantified by high performance liquid chromatography and the results were analyzed by univariate ANOVA and t-test (P<0.05).
Bleach significantly increased the overall release of monomers (P<0.001); TEGDMA was released more than Bis-GMA (P<0.001). Supreme released more TEGDMA compared to Z250 (P<0.001). Bleaching increased the release of this monomer (P<0.001). Increasing both the concentration of H2O2, and the immersion time, increased the release of TEGDMA (P<0.001). Polishing had no effect on release of this monomer (P=0.952). Supreme released more Bis-GMA than Z250 (P=0.000). The more concentrated H2O2 caused more elution of Bis-GMA (P= 0.003); while the effect of immersion time was not significant (P=0.824). Polishing increased the release of Bis-GMA (P=0.001). Neither the type of composite nor Bleaching had any effect on release of UDMA (P=0.972) and (P=0.811) respectively. Immersion duration increased the release of UDMA (P=0.002), as well as polishing (P=0.024).
Bleaching increased the release of monomers. Nanofilled composites released more monomer than the microfilled.
本研究旨在评估漂白对纳米填料复合树脂和微混合复合树脂中单体洗脱的影响。
制备每种复合树脂80个样本（直径5mm，厚度3mm）。固化后，其中一半随机进行抛光处理。每组再分为8个亚组，分别浸泡在水或10%、20%和30%的过氧化氢中3小时或8小时。采用高效液相色谱法定量分析洗脱的双酚A缩水甘油醚（Bis - GMA）、三乙二醇二甲基丙烯酸酯（TEGDMA）、二甲基丙烯酸聚氨酯（UDMA）和双酚A乙氧基二甲基丙烯酸酯（BisEMA），结果通过单因素方差分析和t检验进行分析（P<0.05）。
漂白显著增加了单体的总体释放量（P<0.001）；TEGDMA的释放量多于Bis - GMA（P<0.001）。Supreme复合树脂比Z250复合树脂释放更多的TEGDMA（P<0.001）。漂白增加了该单体的释放量（P<0.001）。过氧化氢浓度和浸泡时间的增加均会增加TEGDMA的释放量（P<0.001）。抛光对该单体的释放无影响（P = 0.952）。Supreme复合树脂比Z250复合树脂释放更多的Bis - GMA（P = 0.000）。过氧化氢浓度越高，Bis - GMA的洗脱量越多（P = 0.003）；而浸泡时间的影响不显著（P = 0.824）。抛光增加了Bis - GMA的释放量（P = 0.001）。复合树脂类型和漂白分别对UDMA的释放均无影响（P = 0.972）和（P = 0.811）。浸泡时间增加了UDMA的释放量（P = 0.002），抛光也增加了UDMA的释放量（P = 0.024）。
漂白增加了单体的释放量。纳米填料复合树脂比微填料复合树脂释放更多的单体。
