Evans Mererid, Powell Ned G
Velindre Cancer Centre, Cardiff, United Kingdom.
Head Neck. 2014 Nov;36(11):1529-33. doi: 10.1002/hed.23792. Epub 2014 Aug 4.
The incidence of oropharyngeal carcinoma is increasing in many countries of the developed world, largely because of cancers caused by infection with human papillomavirus (HPV). HPV-positive patients may ask questions that fall outside the remit of traditional consultations held in head and neck clinics. The purpose of this article is to highlight key messages about HPV and oropharyngeal cancer that are relevant to patients. Key messages include: HPV is a very common virus that transiently infects most people at some point in their lives; HPV infection is transmitted by normal sexual activity and is not a marker of promiscuity or abnormal sexual practices; HPV infections may be acquired many years before a cancer develops and infection does not imply recent infidelity; long-term partners of HPV-positive patients do not seem to be at increased risk of HPV infection.
在许多发达国家,口咽癌的发病率正在上升,这主要是由人乳头瘤病毒(HPV)感染引发的癌症所致。HPV阳性患者可能会提出一些超出头颈诊所传统会诊范围的问题。本文旨在强调与患者相关的关于HPV和口咽癌的关键信息。关键信息包括:HPV是一种非常常见的病毒,大多数人在生命中的某个阶段会短暂感染;HPV感染通过正常性行为传播,并非滥交或异常性行为的标志;HPV感染可能在癌症发生前许多年就已获得,感染并不意味着近期有不忠行为;HPV阳性患者的长期伴侣似乎HPV感染风险并未增加。