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嗜肺潘多拉菌RB38中的群体感应活性。

Quorum sensing activity in Pandoraea pnomenusa RB38.

作者信息

Ee Robson, Lim Yan-Lue, Kin Lin-Xin, Yin Wai-Fong, Chan Kok-Gan

机构信息

Division of Genetics and Molecular Biology, Institute of Biological Sciences, Faculty of Science, University of Malaya, Kuala Lumpur 50603, Malaysia.

出版信息

Sensors (Basel). 2014 Jun 10;14(6):10177-86. doi: 10.3390/s140610177.

DOI:10.3390/s140610177
PMID:24919016
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4118335/
Abstract

Strain RB38 was recovered from a former dumping area in Malaysia. MALDI-TOF mass spectrometry and genomic analysis identified strain RB-38 as Pandoraea pnomenusa. Various biosensors confirmed its quorum sensing properties. High resolution triple quadrupole liquid chromatography-mass spectrometry analysis was subsequently used to characterize the N-acyl homoserine lactone production profile of P. pnomenusa strain RB38, which validated that this isolate produced N-octanoyl homoserine lactone as a quorum sensing molecule. This is the first report of the production of N-octanoyl homoserine lactone by P. pnomenusa strain RB38.

摘要

菌株RB38是从马来西亚一个以前的垃圾倾倒场分离得到的。基质辅助激光解吸电离飞行时间质谱（MALDI-TOF）和基因组分析鉴定菌株RB-38为嗜麦芽窄食单胞菌。各种生物传感器证实了其群体感应特性。随后采用高分辨率三重四极杆液相色谱-质谱联用分析来表征嗜麦芽窄食单胞菌RB38菌株的N-酰基高丝氨酸内酯产生情况，验证了该分离株产生N-辛酰高丝氨酸内酯作为群体感应分子。这是关于嗜麦芽窄食单胞菌RB38菌株产生N-辛酰高丝氨酸内酯的首次报道。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66a/4118335/8ca128261c73/sensors-14-10177f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66a/4118335/b91e93b99c0e/sensors-14-10177f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66a/4118335/10e733d7e5ec/sensors-14-10177f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66a/4118335/8ca128261c73/sensors-14-10177f4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66a/4118335/b91e93b99c0e/sensors-14-10177f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66a/4118335/10e733d7e5ec/sensors-14-10177f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e66a/4118335/8ca128261c73/sensors-14-10177f4.jpg

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本文引用的文献

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Pandoraea sp. RB-44, a novel quorum sensing soil bacterium. Pandoraea sp. RB-44，一种新型的群体感应土壤细菌。
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