At the time of the study, Kelly L. Strutz was with the Department of Maternal and Child Health, Gillings School of Global Public Health, and the Carolina Population Center, University of North Carolina at Chapel Hill. Vijaya K. Hogan, Carolyn Tucker Halpern, and Jon M. Hussey are with the Department of Maternal and Child Health, Anna Maria Siega-Riz is with the Department of Epidemiology and Department of Nutrition, and Chirayath M. Suchindran is with the Department of Biostatistics, Gillings School of Global Public Health, University of North Carolina at Chapel Hill. Anna Maria Siega-Riz, Chirayath M. Suchindran, Carolyn Tucker Halpern, and Jon M. Hussey are also with the Carolina Population Center, University of North Carolina at Chapel Hill.
Am J Public Health. 2014 Aug;104(8):e125-32. doi: 10.2105/AJPH.2014.301904. Epub 2014 Jun 12.
We examined the impact of preconception acute and chronic stressors on offspring birth weight and racial/ethnic birth weight disparities.
We included birth weights for singleton live first (n = 3512) and second (n = 1901) births to White, Mexican-origin Latina, other-origin Latina, and Black women reported at wave IV of the National Longitudinal Study of Adolescent Health (2007-2008; ages 24-32 years). We generated factor scores for preconception acute and chronic stressors from wave I (1994-1995; ages 11-19 years) or wave III (2001-2002; ages 18-26 years) for the same cohort of women.
Linear regression models indicated that chronic stressors, but not acute stressors, were inversely associated with birth weight for both first and second births (b = -192; 95% confidence interval = -270, -113; and b = -180; 95% confidence interval = -315, -45, respectively), and partially explained the disparities in birth weight between the minority racial/ethnic groups and Whites.
Preconception chronic stressors contribute to restricted birth weight and to racial/ethnic birth weight disparities.
本研究旨在探讨孕前急性和慢性应激源对子代出生体重及不同种族/族裔间出生体重差异的影响。
我们纳入了全国青少年健康纵向研究第四波调查（2007-2008 年；年龄 24-32 岁）中报告的 3512 例白人、墨西哥裔拉丁裔、其他族裔拉丁裔和黑人初产妇（单胎活产）以及 1901 例经产妇（单胎活产）的出生体重。我们使用同一队列女性在第一波（1994-1995 年；年龄 11-19 岁）或第三波（2001-2002 年；年龄 18-26 岁）调查中获得的孕前急性和慢性应激源因子评分。
线性回归模型表明，慢性应激源而非急性应激源与初产妇和经产妇的出生体重均呈负相关（初产妇：b=-192；95%置信区间：-270，-113；经产妇：b=-180；95%置信区间：-315，-45），且部分解释了少数族裔与白人之间出生体重差异的原因。
孕前慢性应激源与出生体重受限及不同种族/族裔间出生体重差异有关。
